The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells.
Hochmann, S; Ou, K; Poupardin, R; Mittermeir, M; Textor, M; Ali, S; Wolf, M; Ellinghaus, A; Jacobi, D; Elmiger, JAJ; Donsante, S; Riminucci, M; Schäfer, R; Kornak, U; Klein, O; Schallmoser, K; Schmidt-Bleek, K; Duda, GN; Polansky, JK; Geissler, S; Strunk, D;
Sci Transl Med. 2023; 15(688):eabm7477
Full papers/articles (Journal)

Chondrocyte Isolation from Loose Bodies-An Option for Reducing Donor Site Morbidity for Autologous Chondrocyte Implantation
Textor, M; Hoburg, A; Lehnigk, R; Perka, C; Duda, GN; Reinke, S; Blankenstein, A; Hochmann, S; Stockinger, A; Resch, H; Wolf, M; Strunk, D; Geissler, S
INT J MOL SCI. 2023; 24(2): 1484
Full papers/articles (Journal)

Complement Proteins C5/C5a, Cathepsin D and Prolactin in Chondrocytes: A Possible Crosstalk in the Pathogenesis of Osteoarthritis.
Silawal, S; Wagner, M; Roth, D; Bertsch, T; Schwarz, S; Willauschus, M; Gesslein, M; Triebel, J; Schulze-Tanzil, G;
Cells. 2022; 11(7):
Full papers/articles (Journal)

Highly porous novel chondro-instructive bioactive glass scaffolds tailored for cartilage tissue engineering
Gogele, C; Wiltzsch, S; Lenhart, A; Civilleri, A; Weiger, TM; Schafer-Eckart, K; Minnich, B; Forchheimer, L; Hornfeck, M; Schulze-Tanzil, G
MAT SCI ENG C-MATER. 2021; 130: 112421
Full papers/articles (Journal)

Low pH Attenuates Apoptosis by Suppressing the Volume-Sensitive Outwardly Rectifying (VSOR) Chloride Current in Chondrocytes.
Kittl, M; Winklmayr, M; Preishuber-Pflügl, J; Strobl, V; Gaisberger, M; Ritter, M; Jakab, M;
Front Cell Dev Biol. 2021; 9: 804105
Full papers/articles (Journal)

In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint.
Sturm, L; Schwemberger, B; Menzel, U; Hackel, S; Albers, CE; Plank, C; Rip, J; Alini, M; Traweger, A; Grad, S; Basoli, V
BIOMEDICINES. 2021; 9(7):
Full papers/articles (Journal)

Acid- and Volume-Sensitive Chloride Currents in Human Chondrocytes.
Kittl, M; Winklmayr, M; Helm, K; Lettner, J; Gaisberger, M; Ritter, M; Jakab, M;
Front Cell Dev Biol. 2020; 8: 583131
Full papers/articles (Journal)

3D printing and characterization of human nasoseptal chondrocytes laden dual crosslinked oxidized alginate-gelatin hydrogels for cartilage repair approaches.
Schwarz, S; Kuth, S; Distler, T; Gögele, C; Stölzel, K; Detsch, R; Boccaccini, AR; Schulze-Tanzil, G;
Mater Sci Eng C Mater Biol Appl. 2020; 116: 111189
Full papers/articles (Journal)

Human nasoseptal chondrocytes maintain their differentiated phenotype on PLLA scaffolds produced by thermally induced phase separation and supplemented with bioactive glass 1393.
Conoscenti, G; Carfì Pavia, F; Ongaro, A; Brucato, V; Goegele, C; Schwarz, S; Boccaccini, AR; Stoelzel, K; La Carrubba, V; Schulze-Tanzil, G;
Connect Tissue Res. 2019; 60(4):344-357
Full papers/articles (Journal)

IL-10 Could Play a Role in the Interrelation between Diabetes Mellitus and Osteoarthritis.
Silawal, S; Willauschus, M; Schulze-Tanzil, G; Gögele, C; Geßlein, M; Schwarz, S;
Int J Mol Sci. 2019; 20(3):
Full papers/articles (Journal)

Cartilage regeneration using decellularized cartilage matrix: Long-term comparison of subcutaneous and intranasal placement in a rabbit model.
von Bomhard, A; Elsaesser, A; Riepl, R; Pippich, K; Faust, J; Schwarz, S; Koerber, L; Breiter, R; Rotter, N;
J Craniomaxillofac Surg. 2019; 47(4): 682-694.
Full papers/articles (Journal)

Dose-Dependent Cannabidiol-Induced Elevation of Intracellular Calcium and Apoptosis in Human Articular Chondrocytes.
Winklmayr, M; Gaisberger, M; Kittl, M; Fuchs, J; Ritter, M; Jakab, M;
J Orthop Res. 2019; 37(12):2540-2549
Full papers/articles (Journal)

Cartilage Morphological and Histological Findings After Reconstruction of the Glenoid With an Iliac Crest Bone Graft.
Auffarth, A; Resch, H; Matis, N; Hudelmaier, M; Wirth, W; Forstner, R; Neureiter, D; Traweger, A; Moroder, P;
Am J Sports Med. 2018; 46(5):1039-1045
Full papers/articles (Journal)

Laser surface modification of decellularized extracellular cartilage matrix for cartilage tissue engineering.
Goldberg-Bockhorn, E; Schwarz, S; Subedi, R; Elsässer, A; Riepl, R; Walther, P; Körber, L; Breiter, R; Stock, K; Rotter, N;
Lasers Med Sci. 2018; 33(2):375-384
Full papers/articles (Journal)

Crystal arthritides - gout and calcium pyrophosphate arthritis : Part 1: Epidemiology and pathophysiology.
Schlee, S; Bollheimer, LC; Bertsch, T; Sieber, CC; Härle, P;
Z Gerontol Geriatr. 2018; 51(4): 453-460.
Reviews

PLLA scaffolds produced by thermally induced phase separation (TIPS) allow human chondrocyte growth and extracellular matrix formation dependent on pore size.
Conoscenti, G; Schneider, T; Stoelzel, K; Carfì Pavia, F; Brucato, V; Goegele, C; La Carrubba, V; Schulze-Tanzil, G;
Mater Sci Eng C Mater Biol Appl. 2017; 80:-459
Full papers/articles (Journal)

The role of transient receptor potential channels in joint diseases.
Krupkova, O; Zvick, J; Wuertz-Kozak, K;
Eur Cell Mater. 2017; 34: 180-201.
Full papers/articles (Journal)

Automated bioreactor system for cartilage tissue engineering of human primary nasal septal chondrocytes.
Princz, S; Wenzel, U; Tritschler, H; Schwarz, S; Dettmann, C; Rotter, N; Hessling, M;
Biomed Tech (Berl). 2017; 62(5):481-486
Full papers/articles (Journal)

Impact of expansion and redifferentiation under hypothermia on chondrogenic capacity of cultured human septal chondrocytes.
von Bomhard, A; Faust, J; Elsaesser, AF; Schwarz, S; Pippich, K; Rotter, N
J TISSUE ENG. 2017; 8: 2041731417732655
Full papers/articles (Journal)

Mimicking of Chondrocyte Microenvironment Using In Situ Forming Dendritic Polyglycerol Sulfate-Based Synthetic Polyanionic Hydrogels.
Dey, P; Schneider, T; Chiappisi, L; Gradzielski, M; Schulze-Tanzil, G; Haag, R
MACROMOL BIOSCI. 2016; 16(4): 580-590.
Full papers/articles (Journal)

Characterization of a migrative subpopulation of adult human nasoseptal chondrocytes with progenitor cell features and their potential for in vivo cartilage regeneration strategies.
Elsaesser, AF; Schwarz, S; Joos, H; Koerber, L; Brenner, RE; Rotter, N;
Cell Biosci. 2016; 6: 11
Full papers/articles (Journal)

Establishment of a Cytocompatible Cell-Free Intervertebral Disc Matrix for Chondrogenesis with Human Bone Marrow-Derived Mesenchymal Stromal Cells.
Huang, Z; Kohl, B; Kokozidou, M; Arens, S; Schulze-Tanzil, G
Cells Tissues Organs. 2016; 201(5):354-365
Full papers/articles (Journal)

Chondrogenesis of human bone marrow mesenchymal stromal cells in highly porous alginate-foams supplemented with chondroitin sulfate.
Huang, Z; Nooeaid, P; Kohl, B; Roether, JA; Schubert, DW; Meier, C; Boccaccini, AR; Godkin, O; Ertel, W; Arens, S; Schulze-Tanzil, G
MAT SCI ENG C-MATER. 2015; 50: 160-172.
Full papers/articles (Journal)

Novel bilayer bacterial nanocellulose scaffold supports neocartilage formation in vitro and in vivo.
Martínez Ávila, H; Feldmann, EM; Pleumeekers, MM; Nimeskern, L; Kuo, W; de Jong, WC; Schwarz, S; Müller, R; Hendriks, J; Rotter, N; van Osch, GJ; Stok, KS; Gatenholm, P;
Biomaterials. 2015; 44: 122-133.
Full papers/articles (Journal)

Effects of dendritic polyglycerol sulfate on articular chondrocytes.
Schneider, T; Welker, P; Haag, R; Dernedde, J; Hug, T; Licha, K; Kohl, B; Arens, S; Ertel, W; Schulze-Tanzil, G
Inflamm Res. 2015; 64(11):917-928
Full papers/articles (Journal)

Influence of dendritic polyglycerol sulfates on knee osteoarthritis: an experimental study in the rat osteoarthritis model.
Schneider, T; Welker, P; Licha, K; Haag, R; Schulze-Tanzil, G;
BMC Musculoskelet Disord. 2015; 16(1): 387
Full papers/articles (Journal)

Urine is a novel source of autologous mesenchymal stem cells for patients with epidermolysis bullosa.
Schosserer, M; Reynoso, R; Wally, V; Jug, B; Kantner, V; Weilner, S; Buric, I; Grillari, J; Bauer, JW; Grillari-Voglauer, R;
BMC Res Notes. 2015; 8(1): 767
Full papers/articles (Journal)

Processed xenogenic cartilage as innovative biomatrix for cartilage tissue engineering: effects on chondrocyte differentiation and function.
Schwarz, S; Elsaesser, AF; Koerber, L; Goldberg-Bockhorn, E; Seitz, AM; Bermueller, C; Dürselen, L; Ignatius, A; Breiter, R; Rotter, N;
J Tissue Eng Regen Med. 2015; 9(12): E239-E251.
Full papers/articles (Journal)

Effect of nasal sprays on an in vitro survival and morphology of nasoseptal cartilage.
Stoelzel, K; Kohl, B; Hoyer, M; Meier, C; Szczepek, AJ; Olze, H; Schulze-Tanzil, G;
Eur Arch Otorhinolaryngol. 2015; 272(4):-87.
Full papers/articles (Journal)

Immortalised human mesenchymal stem cells undergo chondrogenic differentiation in alginate and PGA/PLLA scaffolds.
Stölzel, K; Schulze-Tanzil, G; Olze, H; Schwarz, S; Feldmann, EM; Rotter, N;
Cell Tissue Bank. 2015; 16(1):159-170
Full papers/articles (Journal)

In vitro cytotoxicity and in vivo effects of a decellularized xenogeneic collagen scaffold in nasal cartilage repair.
Elsaesser, AF; Bermueller, C; Schwarz, S; Koerber, L; Breiter, R; Rotter, N;
Tissue Eng Part A. 2014; 20(11-12): 1668-1678.
Full papers/articles (Journal)

The influence of IL-10 and TNFα on chondrogenesis of human mesenchymal stromal cells in three-dimensional cultures.
Jagielski, M; Wolf, J; Marzahn, U; Völker, A; Lemke, M; Meier, C; Ertel, W; Godkin, O; Arens, S; Schulze-Tanzil, G;
Int J Mol Sci. 2014; 15(9): 15821-15844.
Full papers/articles (Journal)

Osteochondral articular defect repair using auricle-derived autologous chondrocytes in a rabbit model.
Lohan, A; Marzahn, U; El Sayed, K; Haisch, A; Müller, RD; Kohl, B; Stölzel, K; Ertel, W; John, T; Schulze-Tanzil, G;
Ann Anat. 2014; 196(5): 317-326.
Full papers/articles (Journal)

Marine collagen scaffolds for nasal cartilage repair: prevention of nasal septal perforations in a new orthotopic rat model using tissue engineering techniques.
Bermueller, C; Schwarz, S; Elsaesser, AF; Sewing, J; Baur, N; von Bomhard, A; Scheithauer, M; Notbohm, H; Rotter, N;
Tissue Eng Part A. 2013; 19(19-20): 2201-2214.
Full papers/articles (Journal)

PGA-associated heterotopic chondrocyte cocultures: implications of nasoseptal and auricular chondrocytes in articular cartilage repair.
El Sayed, K; Marzahn, U; John, T; Hoyer, M; Zreiqat, H; Witthuhn, A; Kohl, B; Haisch, A; Schulze-Tanzil, G;
J Tissue Eng Regen Med. 2013; 7(1): 61-72.
Full papers/articles (Journal)

Description of a novel approach to engineer cartilage with porous bacterial nanocellulose for reconstruction of a human auricle.
Feldmann, EM; Sundberg, JF; Bobbili, B; Schwarz, S; Gatenholm, P; Rotter, N;
J Biomater Appl. 2013; 28(4): 626-640.
Full papers/articles (Journal)

Effect of polystyrene and polyether imide cell culture inserts with different roughness on chondrocyte metabolic activity and gene expression profiles of aggrecan and collagen.
König, J; Kohl, B; Kratz, K; Jung, F; Lendlein, A; Ertel, W; Schulze-Tanzil, G;
Clin Hemorheol Microcirc. 2013; 55(4): 52-33.
Full papers/articles (Journal)

Heterotopic and orthotopic autologous chondrocyte implantation using a minipig chondral defect model.
Lohan, A; Marzahn, U; El Sayed, K; Bock, C; Haisch, A; Kohl, B; Stoelzel, K; John, T; Ertel, W; Schulze-Tanzil, G;
Ann Anat. 2013; 195(5): 488-497.
Full papers/articles (Journal)

Hybrid pig versus Gottingen minipig-derived cartilage and chondrocytes show pig line-dependent differences.
Müller, C; Marzahn, U; Kohl, B; El Sayed, K; Lohan, A; Meier, C; Ertel, W; Schulze-Tanzil, G;
Exp Biol Med (Maywood). 2013; 238(11): 1210-1222.
Full papers/articles (Journal)

Influence of fiber orientation in electrospun polymer scaffolds on viability, adhesion and differentiation of articular chondrocytes.
Schneider, T; Kohl, B; Sauter, T; Kratz, K; Lendlein, A; Ertel, W; Schulze-Tanzil, G;
Clin Hemorheol Microcirc. 2012; 52(2-4): 325-336.
Full papers/articles (Journal)

Anaphylatoxin receptors and complement regulatory proteins in human articular and non-articular chondrocytes: interrelation with cytokines.
Schulze-Tanzil, G; Kohl, B; El Sayed, K; Arens, S; Ertel, W; Stölzel, K; John, T;
Cell Tissue Res. 2012; 350(3): 465-475.
Full papers/articles (Journal)

Decellularized cartilage matrix as a novel biomatrix for cartilage tissue-engineering applications.
Schwarz, S; Koerber, L; Elsaesser, AF; Goldberg-Bockhorn, E; Seitz, AM; Dürselen, L; Ignatius, A; Walther, P; Breiter, R; Rotter, N;
Tissue Eng Part A. 2012; 18(21-22):2195-2209
Full papers/articles (Journal)

The dependence of autologous chondrocyte transplantation on varying cellular passage, yield and culture duration.
Salzmann, GM; Sauerschnig, M; Berninger, MT; Kaltenhauser, T; Schönfelder, M; Vogt, S; Wexel, G; Tischer, T; Sudkamp, N; Niemeyer, P; Imhoff, AB; Schöttle, PB;
Biomaterials. 2011; 32(25): 5810-5818.
Full papers/articles (Journal)

Viability, Adhesion and Differentiated Phenotype of Articular Chondrocytes on Degradable Polymers and Electro-Spun Structures Thereof
Schneider, T; Kohl, B; Sauter, T; Becker, T; Kratz, K; Schossig, M; Hiebl, B; Jung, F; Lendlein, A; Ertel, W; Schulze-Tanzil, G
MACROMOL SYMP. 2011; 309-310: 28-39.
Proceedings Papers

The effect of scaffold composition on the early structural characteristics of chondrocytes and expression of adhesion molecules.
Schagemann, JC; Kurz, H; Casper, ME; Stone, JS; Dadsetan, M; Yu-Long, S; Mrosek, EH; Fitzsimmons, JS; O"Driscoll, SW; Reinholz, GG;
BIOMATERIALS. 2010; 31(10): 279-805.
Full papers/articles (Journal)

[Failed pass with sequelae].
Brem, MH; Hennig, FF; Gusinde, J; Olk, A; Blanke, M;
MMW Fortschr Med. 2009; 151(17): 5
Full papers/articles (Journal)

Paracrine effect of transplanted rib chondrocyte spheroids supports formation of secondary cartilage repair tissue.
Gelse, K; Brem, M; Klinger, P; Hess, A; Swoboda, B; Hennig, F; Olk, A;
J Orthop Res. 2009; 27(9):1216-1225
Full papers/articles (Journal)

Cell-Laden and Cell-Free Biopolymer Hydrogel for the Treatment of Osteochondral Defects in a Sheep Model
Schagemann, JC; Erggelet, C; Chung, HW; Lahm, A; Kurz, H; Mrosek, EH
TISSUE ENG PT A. 2009; 15(1): 75-82.
Full papers/articles (Journal)

Activation and dedifferentiation of chondrocytes: implications in cartilage injury and repair.
Schulze-Tanzil, G;
Ann Anat. 2009; 191(4): 325-338.
Reviews

Differing in vitro biology of equine, ovine, porcine and human articular chondrocytes derived from the knee joint: an immunomorphological study.
Schulze-Tanzil, G; Müller, RD; Kohl, B; Schneider, N; Ertel, W; Ipaktchi, K; Hünigen, H; Gemeinhardt, O; Stark, R; John, T;
Histochem Cell Biol. 2009; 131(2): 21-29.
Full papers/articles (Journal)

Interleukin-10 and articular cartilage: experimental therapeutical approaches in cartilage disorders.
Schulze-Tanzil, G; Zreiqat, H; Sabat, R; Kohl, B; Halder, A; Müller, RD; John, T;
Curr Gene Ther. 2009; 9(4): 306-315.
Reviews

Effects of crystalline glucocorticoid triamcinolone acetonide on cultered human supraspinatus tendon cells.
Tempfer, H; Gehwolf, R; Lehner, C; Wagner, A; Mtsariashvili, M; Bauer, HC; Resch, H; Tauber, M;
ACTA ORTHOP. 2009; 80(3): 357-362.
Full papers/articles (Journal)

IL-10 overexpression differentially affects cartilage matrix gene expression in response to TNF-alpha in human articular chondrocytes in vitro.
Müller, RD; John, T; Kohl, B; Oberholzer, A; Gust, T; Hostmann, A; Hellmuth, M; Laface, D; Hutchins, B; Laube, G; Veh, RW; Tschoeke, SK; Ertel, W; Schulze-Tanzil, G;
Cytokine. 2008; 44(3): 377-385.
Full papers/articles (Journal)

Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes.
Wolk, K; Witte, K; Witte, E; Proesch, S; Schulze-Tanzil, G; Nasilowska, K; Thilo, J; Asadullah, K; Sterry, W; Volk, HD; Sabat, R;
J Leukoc Biol. 2008; 83(5): 1181-1193.
Full papers/articles (Journal)

Development and phenotypic characterization of a high density in vitro model of auricular chondrocytes with applications in reconstructive plastic surgery.
Haisch, A; Marzahn, U; Mobasheri, A; Schulze-Tanzil, G; Shakibaei, M;
Histol Histopathol. 2006; 21(5): 4-76.
Full papers/articles (Journal)

[Effect of a Harpagophytum procumbens DC extract on matrix metalloproteinases in human chondrocytes in vitro].
Schulze-Tanzil, G; Hansen, C; Shakibaei, M;
Arzneimittelforschung. 2004; 54(4): 213-220.
Full papers/articles (Journal)

Prognostic relevance of cell biologic and biochemical features in conventional chondrosarcomas.
Aigner, T; Müller, S; Neureiter, D; Illstrup, DM; Kirchner, T; Björnsson, J;
Cancer. 2002; 94(8): 2273-2281.
Full papers/articles (Journal)

Redifferentiation of dedifferentiated human chondrocytes in high-density cultures.
Schulze-Tanzil, G; de Souza, P; Villegas Castrejon, H; John, T; Merker, HJ; Scheid, A; Shakibaei, M;
Cell Tissue Res. 2002; 308(3): 371-379.
Full papers/articles (Journal)

Effects of the antirheumatic remedy hox alpha--a new stinging nettle leaf extract--on matrix metalloproteinases in human chondrocytes in vitro.
Schulze-Tanzil, G; de, SP; Behnke, B; Klingelhoefer, S; Scheid, A; Shakibaei, M;
Histol Histopathol. 2002; 17(2): 477-485.
Full papers/articles (Journal)

Co-localization of integrins and matrix metalloproteinases in the extracellular matrix of chondrocyte cultures.
Schulze-Tanzil, G; de Souza, P; Merker, HJ; Shakibaei, M;
Histol Histopathol. 2001; 16(4): 1081-1089.
Full papers/articles (Journal)

Inhibition of mitogen-activated protein kinase kinase induces apoptosis of human chondrocytes.
Shakibaei, M; Schulze-Tanzil, G; de Souza, P; John, T; Rahmanzadeh, M; Rahmanzadeh, R; Merker, HJ;
J Biol Chem. 2001; 276(16): 1328-1394.
Full papers/articles (Journal)