Publications
chosen keywordREGULATORY VOLUME DECREASE
O-GlcNAcylation Suppresses the Ion Current IClswell by Preventing the Binding of the Protein ICln to α-Integrin.
Costa, R; Remigante, A; Civello, DA; Bernardinelli, E; Szabo, Z; Morabito, R; Marino, A; Sarikas, A; Patsch, W; Paulmichl, M; Janaky, T; Miseta, A; Nagy, T; Dossena, S
FRONT CELL DEV BIOL. 2020; 8: 607080
Full papers/articles (Journal)
Cadmium affects osmotic phase and regulatory volume decrease in cultured human embryonic kidney cells
Morabito, R; Remigante, A; Costa, R; Dossena, S; La Spada, G; Marino, A
J BIOL RES-BOLL SOC. 2016; 89(1): 12-19.
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The molecular and functional interaction between ICln and HSPC038 proteins modulates the regulation of cell volume.
Dossena, S; Gandini, R; Tamma, G; Vezzoli, V; Nofziger, C; Tamplenizza, M; Salvioni, E; Bernardinelli, E; Meyer, G; Valenti, G; Wolf-Watz, M; Fürst, J; Paulmichl, M;
J Biol Chem. 2011; 286(47):40659-40670
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EGF stimulates IClswell by a redistribution of proteins involved in cell volume regulation.
Tamma, G; Dossena, S; Nofziger, C; Valenti, G; Svelto, M; Paulmichl, M;
CELL PHYSIOL BIOCHEM. 2011; 28(6): 1191-1202.
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Quaternary structure assessment of ICln by fluorescence resonance energy transfer (FRET) in vivo.
Schmidt, S; Jakab, M; Costa, I; Fürst, J; Ravasio, A; Paulmichl, M; Botta, G; Ritter, M;
Cell Physiol Biochem. 2009; 23(4-6):397-406
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LSm4 associates with the plasma membrane and acts as a co-factor in cell volume regulation.
Gandini, R; Dossena, S; Vezzoli, V; Tamplenizza, M; Salvioni, E; Ritter, M; Paulmichl, M; Furst, J;
CELL PHYSIOL BIOCHEM. 2008; 22(5-6): 579-590.
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Hypotonicity and ethanol modulate BK channel activity and chloride currents in GH4/C1 pituitary tumour cells.
Jakab, M; Schmidt, S; Grundbichler, M; Paulmichl, M; Hermann, A; Weiger, T; Ritter, M;
Acta Physiol (Oxf). 2006; 187(1-2):51-59
Reviews
ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4.
Fürst, J; Schedlbauer, A; Gandini, R; Garavaglia, ML; Saino, S; Gschwentner, M; Sarg, B; Lindner, H; Jakab, M; Ritter, M; Bazzini, C; Botta, G; Meyer, G; Kontaxis, G; Tilly, BC; Konrat, R; Paulmichl, M;
J Biol Chem. 2005; 280(35):31276-31282
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Volume-regulated Cl- channels in human pleural mesothelioma cells.
Meyer, G; Rodighiero, S; Guizzardi, F; Bazzini, C; Bottà, G; Bertocchi, C; Garavaglia, L; Dossena, S; Manfredi, R; Sironi, C; Catania, A; Paulmichl, M;
FEBS Lett. 2004; 559(1-3):4-50
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Cell swelling stimulates cytosol to membrane transposition of ICln.
Ritter, M; Ravasio, A; Jakab, M; Chwatal, S; Fürst, J; Laich, A; Gschwentner, M; Signorelli, S; Burtscher, C; Eichmüller, S; Paulmichl, M;
J Biol Chem. 2003; 278(50):50163-50174
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Molecular and functional aspects of anionic channels activated during regulatory volume decrease in mammalian cells.
Fürst, J; Gschwentner, M; Ritter, M; Bottà, G; Jakab, M; Mayer, M; Garavaglia, L; Bazzini, C; Rodighiero, S; Meyer, G; Eichmüller, S; Wöll, E; Paulmichl, M;
Pflugers Arch. 2002; 444(1-2): 1-25.
Reviews
Simvastatin inhibits malignant transformation following expression of the Ha-ras oncogene in NIH 3T3 fibroblasts.
Fürst, J; Haller, T; Chwatal, S; Wöll, E; Dartsch, PC; Gschwentner, M; Dienstl, A; Zwierzina, H; Lang, F; Paulmichl, M; Ritter, M;
Cell Physiol Biochem. 2002; 12(1): 19-30.
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Mechanisms sensing and modulating signals arising from cell swelling
Jakab, M; Furst, J; Gschwentner, M; Botta, G; Garavaglia, ML; Bazzini, C; Rodighiero, S; Meyer, G; Eichmuller, S; Woll, W; Chwatal, S; Ritter, M; Paulmichl, M
CELL PHYSIOL BIOCHEM. 2002; 12(5-6): 235-258.
Reviews
Functional reconstitution of ICln in lipid bilayers.
Fürst, J; Bazzini, C; Jakab, M; Meyer, G; König, M; Gschwentner, M; Ritter, M; Schmarda, A; Bottà, G; Benz, R; Deetjen, P; Paulmichl, M;
Pflugers Arch. 2000; 440(1): 100-115.
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Structure and function of the ion channel ICln.
Fürst, J; Jakab, M; König, M; Ritter, M; Gschwentner, M; Rudzki, J; Danzl, J; Mayer, M; Burtscher, CM; Schirmer, J; Maier, B; Nairz, M; Chwatal, S; Paulmichl, M;
CELL PHYSIOL BIOCHEM. 2000; 10(5-6): 329-334.
Reviews
Swelling-induced taurine release without chloride channel activity in Xenopus laevis oocytes expressing anion channels and transporters.
Stegen, C; Matskevich, I; Wagner, CA; Paulmichl, M; Lang, F; Bröer, S;
Biochim Biophys Acta. 2000; 1467(1): 91-100.
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Characterization of the human gene coding for the swelling-dependent chloride channel ICln at position 11q13.5-14.1 (CLNS1A) and further characterization of the chromosome 6 (CLNS1B) localization.
Nagl, UO; Erdel, M; Bergmann, F; Oehl, B; Scandella, E; Musante, L; Galietta, LJ; Gschwentner, M; Fürst, J; Schmarda, A; Hofer, S; Utermann, G; Deetjen, P; Paulmichl, M;
Gene. 1998; 209(1-2): 59-63.
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Cloning of the swelling-dependent chloride channel I-Cln homologue from zebra fish
Schmarda, A; Nagl, UO; Gschwentner, M; Furst, J; Hofer, S; Deetjen, P; Paulmichl, M
CELL PHYSIOL BIOCHEM. 1997; 7(5): 298-302.
Notes
Blockade of swelling-induced chloride channels by phenol derivatives.
Gschwentner, M; Jungwirth, A; Hofer, S; Wöll, E; Ritter, M; Susanna, A; Schmarda, A; Reibnegger, G; Pinggera, GM; Leitinger, M; Frick, J; Deetjen, P; Paulmichl, M;
Br J Pharmacol. 1996; 118(1): 41-48.
Full papers/articles (Journal)
ICln: a chloride channel paramount for cell volume regulation.
Gschwentner, M; Susanna, A; Schmarda, A; Laich, A; Nagl, UO; Ellemunter, H; Deetjen, P; Frick, J; Paulmichl, M;
J Allergy Clin Immunol. 1996; 98(5 Pt 2): S98-101.
Reviews
Chromosomal localization of the genes (CLNS1A and CLNS1B) coding for the swelling-dependent chloride channel ICln.
Nagl, UO; Erdel, M; Schmarda, A; Seri, M; Pinggera, GM; Gschwentner, M; Duba, C; Galietta, LJ; Deetjen, P; Utermann, G; Paulmichl, M;
Genomics. 1996; 38(3): 438-441.
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Fluorescence-optical measurements of chloride movements in cells using the membrane-permeable dye diH-MEQ.
Wöll, E; Gschwentner, M; Fürst, J; Hofer, S; Buemberger, G; Jungwirth, A; Frick, J; Deetjen, P; Paulmichl, M;
Pflugers Arch. 1996; 432(3): 486-493.
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Antisense oligonucleotides suppress cell-volume-induced activation of chloride channels.
Gschwentner, M; Nagl, UO; Wöll, E; Schmarda, A; Ritter, M; Paulmichl, M;
Pflugers Arch. 1995; 430(4): 464-470.
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Structure-function relation of a cloned epithelial chloride channel.
Gschwentner, M; Nagl, UO; Schmarda, A; Wöll, E; Ritter, M; Waitz, W; Deetjen, P; Paulmichl, M;
Ren Physiol Biochem. 1994; 17(3-4): 148-152.
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