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Research Database PMU-SQQUID

Publications

chosen keywordNeurogenesis


Stroke Accelerates and Uncouples Intrinsic and Synaptic Excitability Maturation of Mouse Hippocampal DCX
Ceanga, M; Keiner, S; Grünewald, B; Haselmann, H; Frahm, C; Couillard-Després, S; Witte, OW; Redecker, C; Geis, C; Kunze, A;
J Neurosci. 2019; 39(9): 1755-1766.
Originalarbeiten (Zeitschrift)
The leukotriene signaling pathway: a druggable target in Alzheimer"s disease.
Michael, J; Marschallinger, J; Aigner, L;
Drug Discov Today. 2019; 24(2):505-516
Übersichtsarbeiten
Neuroplasticity, limbic neuroblastosis and neuro-regenerative disorders.
Kandasamy, M; Aigner, L
NEURAL REGEN RES. 2018; 13(8): 1322-1326.
Übersichtsarbeiten
Reactive Neuroblastosis in Huntington's Disease: A Putative Therapeutic Target for Striatal Regeneration in the Adult Brain
Kandasamy, M; Aigner, L
FRONT CELL NEUROSCI. 2018; 12: 37
Originalarbeiten (Zeitschrift)
Neurogenesis upregulation on the healthy hemisphere after stroke enhances compensation for age-dependent decrease of basal neurogenesis.
Adamczak, J; Aswendt, M; Kreutzer, C; Rotheneichner, P; Riou, A; Selt, M; Beyrau, A; Uhlenküken, U; Diedenhofen, M; Nelles, M; Aigner, L; Couillard-Despres, S; Hoehn, M;
Neurobiol Dis. 2017; 99: 47-57.
Originalarbeiten (Zeitschrift)
In vivo bioluminescence imaging of neurogenesis - the role of the blood brain barrier in an experimental model of Parkinson"s disease.
Fricke, IB; Schelhaas, S; Zinnhardt, B; Viel, T; Hermann, S; Couillard-Després, S; Jacobs, AH;
Eur J Neurosci. 2017; 45(7): 975-986.
Originalarbeiten (Zeitschrift)
The TgF-beta system as a Potential Pathogenic Player in Disease Modulation of amyotrophic lateral sclerosis
Peters, S; Zitzelsperger, E; Kuespert, S; Iberl, S; Heydn, R; Johannesen, S; Petri, S; Aigner, L; Thal, DR; Hermann, A; Weishaupt, JH; Bruun, TH; Bogdahn, U
FRONT NEUROL. 2017; 8: 669
Originalarbeiten (Zeitschrift)
Tamoxifen Activation of Cre-Recombinase Has No Persisting Effects on Adult Neurogenesis or Learning and Anxiety.
Rotheneichner, P; Romanelli, P; Bieler, L; Pagitsch, S; Zaunmair, P; Kreutzer, C; König, R; Marschallinger, J; Aigner, L; Couillard-Després, S;
Front Neurosci. 2017; 11: 27
Originalarbeiten (Zeitschrift)
Allergy Enhances Neurogenesis and Modulates Microglial Activation in the Hippocampus.
Klein, B; Mrowetz, H; Thalhamer, J; Scheiblhofer, S; Weiss, R; Aigner, L;
Front Cell Neurosci. 2016; 10: 169
Originalarbeiten (Zeitschrift)
The maternal brain under stress: Consequences for adaptive peripartum plasticity and its potential functional implications.
Slattery, DA; Hillerer, KM;
Front Neuroendocrinol. 2016; 41: 114-128.
Originalarbeiten (Zeitschrift)
Early Changes in Hippocampal Neurogenesis in Transgenic Mouse Models for Alzheimerxxxs Disease
Unger, MS; Marschallinger, J; Kaindl, J; Hofling, C; Rossner, S; Heneka, MT; Van der Linden, A; Aigner, L
MOL NEUROBIOL. 2016; 53(8): 5796-5806.
Originalarbeiten (Zeitschrift)
Analysis of Neurogenesis during Experimental Autoimmune Encephalomyelitis Reveals Pitfalls of Bioluminescence Imaging.
Ayzenberg, I; Schlevogt, S; Metzdorf, J; Stahlke, S; Pedreitturia, X; Hunfeld, A; Couillard-Despres, S; Kleiter, I;
PLoS One. 2015; 10(3): e0118550
Originalarbeiten (Zeitschrift)
Reduction in subventricular zone-derived olfactory bulb neurogenesis in a rat model of Huntington"s disease is accompanied by striatal invasion of neuroblasts.
Kandasamy, M; Rosskopf, M; Wagner, K; Klein, B; Couillard-Despres, S; Reitsamer, HA; Stephan, M; Nguyen, HP; Riess, O; Bogdahn, U; Winkler, J; von Horsten, S; Aigner, L
PLoS One. 2015; 10(2):e0116069
Originalarbeiten (Zeitschrift)
Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells.
Kazanis, I; Feichtner, M; Lange, S; Rotheneichner, P; Hainzl, S; Öller, M; Schallmoser, K; Rohde, E; Reitsamer, HA; Couillard-Despres, S; Bauer, HC; Franklin, RJ; Aigner, L; Rivera, FJ;
Exp Neurol. 2015; 269: 75-89.
Originalarbeiten (Zeitschrift)
The L-type calcium channel Cav1.3 is required for proper hippocampal neurogenesis and cognitive functions.
Marschallinger, J; Sah, A; Schmuckermair, C; Unger, M; Rotheneichner, P; Kharitonova, M; Waclawiczek, A; Gerner, P; Jaksch-Bogensperger, H; Berger, S; Striessnig, J; Singewald, N; Couillard-Despres, S; Aigner, L;
Cell Calcium. 2015; 58(6): 606-616.
Originalarbeiten (Zeitschrift)
Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.
Marschallinger, J; Schäffner, I; Klein, B; Gelfert, R; Rivera, FJ; Illes, S; Grassner, L; Janssen, M; Rotheneichner, P; Schmuckermair, C; Coras, R; Boccazzi, M; Chishty, M; Lagler, FB; Renic, M; Bauer, HC; Singewald, N; Blümcke, I; Bogdahn, U; Couillard-Despres, S; Lie, DC; Abbracchio, MP; Aigner, L;
Nat Commun. 2015; 6: 8466
Originalarbeiten (Zeitschrift)
Neurodifferentiating potential of 8-prenylnaringenin and related compounds in neural precursor cells and correlation with estrogen-like activity.
Urmann, C; Oberbauer, E; Couillard-Després, S; Aigner, L; Riepl, H;
Planta Med. 2015; 81(4):305-311
Originalarbeiten (Zeitschrift)
The Maternal Brain: An Organ with Peripartal Plasticity.
Hillerer, KM; Jacobs, VR; Fischer, T; Aigner, L;
Neural Plast. 2014; 2014: 574159
Originalarbeiten (Zeitschrift)
Lactation-induced reduction in hippocampal neurogenesis is reversed by repeated stress exposure.
Hillerer, KM; Neumann, ID; Couillard-Despres, S; Aigner, L; Slattery, DA;
Hippocampus. 2014; 24(6):673-683
Originalarbeiten (Zeitschrift)
Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis.
Marschallinger, J; Krampert, M; Couillard-Despres, S; Heuchel, R; Bogdahn, U; Aigner, L;
Exp Gerontol. 2014; 57: 149-154.
Originalarbeiten (Zeitschrift)
Hippocampal Neurogenesis and Antidepressive Therapy: Shocking Relations
Rotheneichner, P; Lange, S; O'Sullivan, A; Marschallinger, J; Zaunmair, P; Geretsegger, C; Aigner, L; Couillard-Despres, S
NEURAL PLAST. 2014; 2014: 723915
Übersichtsarbeiten
Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development.
Cappello, S; Gray, MJ; Badouel, C; Lange, S; Einsiedler, M; Srour, M; Chitayat, D; Hamdan, FF; Jenkins, ZA; Morgan, T; Preitner, N; Uster, T; Thomas, J; Shannon, P; Morrison, V; Di Donato, N; Van Maldergem, L; Neuhann, T; Newbury-Ecob, R; Swinkells, M; Terhal, P; Wilson, LC; Zwijnenburg, PJ; Sutherland-Smith, AJ; Black, MA; Markie, D; Michaud, JL; Simpson, MA; Mansour, S; McNeill, H; Götz, M; Robertson, SP;
Nat Genet. 2013; 45(11): 1300-1308.
Originalarbeiten (Zeitschrift)
Hippocampal neurogenesis and ageing.
Couillard-Després, S;
Curr Top Behav Neurosci. 2013; 15:343-355
Übersichtsarbeiten
Sex-dependent regulation of hippocampal neurogenesis under basal and chronic stress conditions in rats.
Hillerer, KM; Neumann, ID; Couillard-Despres, S; Aigner, L; Slattery, DA;
Hippocampus. 2013; 23(6):476-487
Originalarbeiten (Zeitschrift)
Chroman-like cyclic prenylflavonoids promote neuronal differentiation and neurite outgrowth and are neuroprotective.
Oberbauer, E; Urmann, C; Steffenhagen, C; Bieler, L; Brunner, D; Furtner, T; Humpel, C; Bäumer, B; Bandtlow, C; Couillard-Despres, S; Rivera, FJ; Riepl, H; Aigner, L;
J Nutr Biochem. 2013; 24(11):1953-1962
Originalarbeiten (Zeitschrift)
Neurogenesis and neuronal regeneration in status epilepticus.
Rotheneichner, P; Marschallinger, J; Couillard-Despres, S; Aigner, L;
Epilepsia. 2013; 54 Suppl 6:40-42
Übersichtsarbeiten
Stem cell metabolic and spectroscopic profiling.
Sander, PR; Hau, P; Koch, S; Schutze, K; Bogdahn, U; Kalbitzer, HR; Aigner, L
Trends Biotechnol. 2013; 31(3):204-213
Übersichtsarbeiten
Congruence of vascular network remodeling and neuronal dispersion in the hippocampus of reelin-deficient mice.
Lindhorst, T; Kurz, H; Sibbe, M; Meseke, M; Förster, E;
Histochem Cell Biol. 2012; 137(5):62-39
Originalarbeiten (Zeitschrift)
SoxC Transcription Factors Are Required for Neuronal Differentiation in Adult Hippocampal Neurogenesis
Mu, LF; Berti, L; Masserdotti, G; Covic, M; Michaelidis, TM; Doberauer, K; Merz, K; Rehfeld, F; Haslinger, A; Wegner, M; Sock, E; Lefebvre, V; Couillard-Despres, S; Aigner, L; Berninger, B; Lie, DC
J NEUROSCI. 2012; 32(9): 3067-3080.
Originalarbeiten (Zeitschrift)
Anxiety- rather than depression-like behavior is associated with adult neurogenesis in a female mouse model of higher trait anxiety- and comorbid depression-like behavior.
Sah, A; Schmuckermair, C; Sartori, SB; Gaburro, S; Kandasamy, M; Irschick, R; Klimaschewski, L; Landgraf, R; Aigner, L; Singewald, N
Transl Psychiatry. 2012; 2:e171
Originalarbeiten (Zeitschrift)
In situ labeling and imaging of endogenous neural stem cell proliferation and migration.
Vande Velde, G; Couillard-Després, S; Aigner, L; Himmelreich, U; van der Linden, A;
WIRES NANOMED NANOBI. 2012; 4(6): 663-679.
Übersichtsarbeiten
In vivo imaging of adult neurogenesis
Couillard-Despres, S; Aigner, L
EUR J NEUROSCI. 2011; 33(6): 1037-1044.
Originalarbeiten (Zeitschrift)
Neurogenesis, Cellular Plasticity and Cognition: The Impact of Stem Cells in the Adult and Aging Brain - A Mini-Review
Couillard-Despres, S; Iglseder, B; Aigner, L
GERONTOLOGY. 2011; 57(6): 559-564.
Übersichtsarbeiten
In vivo monitoring of adult neurogenesis in health and disease.
Couillard-Despres, S; Vreys, R; Aigner, L; Van der Linden, A;
Front Neurosci. 2011; 5: 67
Übersichtsarbeiten
Transmigration of melanoma cells through the blood-brain barrier: role of endothelial tight junctions and melanoma-released serine proteases.
Fazakas, C; Wilhelm, I; Nagyoszi, P; Farkas, AE; Haskó, J; Molnár, J; Bauer, H; Bauer, HC; Ayaydin, F; Dung, NT; Siklós, L; Krizbai, IA;
PLoS One. 2011; 6(6): e20758
Originalarbeiten (Zeitschrift)
Inhibition of leukotriene receptors boosts neural progenitor proliferation.
Huber, C; Marschallinger, J; Tempfer, H; Furtner, T; Couillard-Despres, S; Bauer, HC; Rivera, FJ; Aigner, L;
Cell Physiol Biochem. 2011; 28(5):793-804
Originalarbeiten (Zeitschrift)
The dark side of BrdU in neural stem cell biology: detrimental effects on cell cycle, differentiation and survival.
Lehner, B; Sandner, B; Marschallinger, J; Lehner, C; Furtner, T; Couillard-Despres, S; Rivera, FJ; Brockhoff, G; Bauer, HC; Weidner, N; Aigner, L;
Cell Tissue Res. 2011; 345(3):313-328
Originalarbeiten (Zeitschrift)
A new role for interferon gamma in neural stem/precursor cell dysregulation.
Walter, J; Honsek, SD; Illes, S; Wellen, JM; Hartung, HP; Rose, CR; Dihné, M;
Mol Neurodegener. 2011; 6: 18
Originalarbeiten (Zeitschrift)
Heterogeneity and Fgf dependence of adult neural progenitors in the zebrafish telencephalon.
Ganz, J; Kaslin, J; Hochmann, S; Freudenreich, D; Brand, M;
Glia. 2010; 58(11):1345-1363
Originalarbeiten (Zeitschrift)
Stem cell quiescence in the hippocampal neurogenic niche is associated with elevated transforming growth factor-beta signaling in an animal model of Huntington disease.
Kandasamy, M; Couillard-Despres, S; Raber, KA; Stephan, M; Lehner, B; Winner, B; Kohl, Z; Rivera, FJ; Nguyen, HP; Riess, O; Bogdahn, U; Winkler, J; von Hörsten, S; Aigner, L;
J Neuropathol Exp Neurol. 2010; 69(7):717-728
Originalarbeiten (Zeitschrift)
A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons.
Zhang, J; Giesert, F; Kloos, K; Vogt Weisenhorn, DM; Aigner, L; Wurst, W; Couillard-Despres, S;
BMC Neurosci. 2010; 11:158
Originalarbeiten (Zeitschrift)
GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus.
Jagasia, R; Steib, K; Englberger, E; Herold, S; Faus-Kessler, T; Saxe, M; Gage, FH; Song, H; Lie, DC;
J Neurosci. 2009; 29(25): 7966-7977.
Originalarbeiten (Zeitschrift)
Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein.
Marxreiter, F; Nuber, S; Kandasamy, M; Klucken, J; Aigner, R; Burgmayer, R; Couillard-Despres, S; Riess, O; Winkler, J; Winner, B;
EUR J NEUROSCI. 2009; 29(5): 87-90.
Originalarbeiten (Zeitschrift)
Protein tyrosine phosphatases expression during development of mouse superior colliculus.
Reinhard, J; Horvat-Bröcker, A; Illes, S; Zaremba, A; Knyazev, P; Ullrich, A; Faissner, A;
Exp Brain Res. 2009; 199(3-4): 2-97.
Originalarbeiten (Zeitschrift)
Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model
Winner, B; Desplats, P; Hagl, C; Klucken, J; Aigner, R; Ploetz, S; Laemke, J; Karl, A; Aigner, L; Masliah, E; Buerger, E; Winkler, J
EXP NEUROL. 2009; 219(2): 543-552.
Originalarbeiten (Zeitschrift)
TGF-beta in neural stem cells and in tumors of the central nervous system
Aigner, L; Bogdahn, U
CELL TISSUE RES. 2008; 331(1): 225-241.
Übersichtsarbeiten
Dopaminergic lesion enhances growth factor-induced striatal neuroblast migration.
Winner, B; Couillard-Despres, S; Geyer, M; Aigner, R; Bogdahn, U; Aigner, L; Kuhn, HG; Winkler, J;
J Neuropathol Exp Neurol. 2008; 67(2): 105-116.
Originalarbeiten (Zeitschrift)
Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis.
Winner, B; Rockenstein, E; Lie, DC; Aigner, R; Mante, M; Bogdahn, U; Couillard-Despres, S; Masliah, E; Winkler, J;
Neurobiol Aging. 2008; 29(6): 913-925.
Originalarbeiten (Zeitschrift)
Physical activity fails to rescue hippocampal neurogenesis deficits in the R6/2 mouse model of Huntington"s disease.
Kohl, Z; Kandasamy, M; Winner, B; Aigner, R; Gross, C; Couillard-Despres, S; Bogdahn, U; Aigner, L; Winkler, J;
Brain Res. 2007; 1155:24-33
Originalarbeiten (Zeitschrift)
Mirtazapine monotherapy versus combination therapy with mirtazapine and aripiprazole in depressed patients without psychotic features: a 4-week open-label parallel-group study.
Schüle, C; Baghai, TC; Eser, D; Hecht, S; Hermisson, I; Born, C; Häfner, S; Nothdurfter, C; Rupprecht, R;
World J Biol Psychiatry. 2007; 8(2):11-22
Originalarbeiten (Zeitschrift)
Targeted transgene expression in neuronal precursors: watching young neurons in the old brain.
Couillard-Despres, S; Winner, B; Karl, C; Lindemann, G; Schmid, P; Aigner, R; Laemke, J; Bogdahn, U; Winkler, J; Bischofberger, J; Aigner, L;
Eur J Neurosci. 2006; 24(6): 153-145.
Originalarbeiten (Zeitschrift)
Systemic application of granulocyte-colony stimulating factor and stem cell factor exacerbates excitotoxic brain injury in newborn mice.
Keller, M; Simbruner, G; Górna, A; Urbanek, M; Tinhofer, I; Griesmaier, E; Sarkozy, G; Schwendimann, L; Gressens, P;
Pediatr Res. 2006; 59(4 Pt 1):549-553
Originalarbeiten (Zeitschrift)
Mesenchymal stem cells instruct oligodendrogenic fate decision on adult neural stem cells.
Rivera, FJ; Couillard-Despres, S; Pedre, X; Ploetz, S; Caioni, M; Lois, C; Bogdahn, U; Aigner, L;
Stem Cells. 2006; 24(10):2209-2219
Originalarbeiten (Zeitschrift)
Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb.
Winner, B; Geyer, M; Couillard-Despres, S; Aigner, R; Bogdahn, U; Aigner, L; Kuhn, G; Winkler, J;
Exp Neurol. 2006; 197(1):113-121
Originalarbeiten (Zeitschrift)
Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1.
Barnabé-Heider, F; Wasylnka, JA; Fernandes, KJ; Porsche, C; Sendtner, M; Kaplan, DR; Miller, FD;
Neuron. 2005; 48(2): 253-265.
Originalarbeiten (Zeitschrift)
Doublecortin expression levels in adult brain reflect neurogenesis.
Couillard-Despres, S; Winner, B; Schaubeck, S; Aigner, R; Vroemen, M; Weidner, N; Bogdahn, U; Winkler, J; Kuhn, HG; Aigner, L;
Eur J Neurosci. 2005; 21(1):-14
Originalarbeiten (Zeitschrift)
Neuronal precursor-specific activity of a human doublecortin regulatory sequence.
Karl, C; Couillard-Despres, S; Prang, P; Munding, M; Kilb, W; Brigadski, T; Plötz, S; Mages, W; Luhmann, H; Winkler, J; Bogdahn, U; Aigner, L;
J Neurochem. 2005; 92(2):264-282
Originalarbeiten (Zeitschrift)
Mitotic impairment by doublecortin is diminished by doublecortin mutations found in patients.
Couillard-Despres, S; Uyanik, G; Ploetz, S; Karl, C; Koch, H; Winkler, J; Aigner, L;
Neurogenetics. 2004; 5(2): 83-93.
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Transient expression of doublecortin during adult neurogenesis.
Brown, JP; Couillard-Després, S; Cooper-Kuhn, CM; Winkler, J; Aigner, L; Kuhn, HG;
J Comp Neurol. 2003; 467(1): 1-10.
Originalarbeiten (Zeitschrift)