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Forschungsdatenbank PMU-SQQUID

Publikationen

Gewähltes Keyword: blood-brain barrier


High dose vitamin D exacerbates central nervous system autoimmunity by raising T-cell excitatory calcium.
Häusler, D; Torke, S; Peelen, E; Bertsch, T; Djukic, M; Nau, R; Larochelle, C; Zamvil, SS; Brück, W; Weber, MS;
Brain. 2019;
Originalarbeiten (Zeitschrift)
The leukotriene signaling pathway: a druggable target in Alzheimer"s disease.
Michael, J; Marschallinger, J; Aigner, L;
Drug Discov Today. 2019; 24(2):505-516
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Pericytes in Multiple Sclerosis.
Rivera, FJ; Hinrichsen, B; Silva, ME
Adv Exp Med Biol. 2019; 1147:167-187
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Intravenous brivaracetam in status epilepticus: A retrospective single-center study.
Kalss, G; Rohracher, A; Leitinger, M; Pilz, G; Novak, HF; Neuray, C; Kreidenhuber, R; Höfler, J; Kuchukhidze, G; Trinka, E;
Epilepsia. 2018; 59 Suppl 2: 228-233.
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Tight Junctions of the Blood-Brain Barrier - A Molecular Gatekeeper.
Bauer, H; Traweger, A;
CNS Neurol Disord Drug Targets. 2016; 15(9): 1016-1029.
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Pharmaceutical Targeting of the Brain.
Krizbai, IA; Nyúl-Tóth, Á; Bauer, HC; Farkas, AE; Traweger, A; Haskó, J; Bauer, H; Wilhelm, I;
Curr Pharm Des. 2016; 22(35):5442-5462
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The blood-tendon barrier: identification and characterisation of a novel tissue barrier in tendon blood vessels.
Lehner, C; Gehwolf, R; Ek, JC; Korntner, S; Bauer, H; Bauer, HC; Traweger, A; Tempfer, H;
Eur Cell Mater. 2016; 31:296-311
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Analysis of Neurogenesis during Experimental Autoimmune Encephalomyelitis Reveals Pitfalls of Bioluminescence Imaging.
Ayzenberg, I; Schlevogt, S; Metzdorf, J; Stahlke, S; Pedreitturia, X; Hunfeld, A; Couillard-Despres, S; Kleiter, I;
PLoS One. 2015; 10(3): e0118550
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Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia.
Ek, CJ; D'Angelo, B; Baburamani, AA; Lehner, C; Leverin, AL; Smith, PLP; Nilsson, H; Svedin, P; Hagberg, H; Mallard, C
J Cereb Blood Flow Metab. 2015; 35(5):818-827
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Glutamate-mediated upregulation of the multidrug resistance protein 2 in porcine and human brain capillaries.
Luna-Munguia, H; Salvamoser, JD; Pascher, B; Pieper, T; Getzinger, T; Kudernatsch, M; Kluger, G; Potschka, H;
J Pharmacol Exp Ther. 2015; 352(2): 368-378.
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Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.
Marschallinger, J; Schäffner, I; Klein, B; Gelfert, R; Rivera, FJ; Illes, S; Grassner, L; Janssen, M; Rotheneichner, P; Schmuckermair, C; Coras, R; Boccazzi, M; Chishty, M; Lagler, FB; Renic, M; Bauer, HC; Singewald, N; Blümcke, I; Bogdahn, U; Couillard-Despres, S; Lie, DC; Abbracchio, MP; Aigner, L;
Nat Commun. 2015; 6: 8466
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Glutamate-Mediated Down-Regulation of the Multidrug-Resistance Protein BCRP/ABCG2 in Porcine and Human Brain Capillaries.
Salvamoser, JD; Avemary, J; Luna-Munguia, H; Pascher, B; Getzinger, T; Pieper, T; Kudematsch, M; Kluger, G; Potschka, H
Mol Pharm. 2015; 12(6):2049-2060
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"You Shall Not Pass"-tight junctions of the blood brain barrier
Bauer, HC; Krizbai, IA; Bauer, H; Traweger, A
FRONT NEUROSCI-SWITZ. 2014; 8:
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The rights and wrongs of blood-brain barrier permeability studies: a walk through 100 years of history
Saunders, NR; Dreifuss, JJ; Dziegielewska, KM; Johansson, PA; Habgood, MD; Mollgard, K; Bauer, HC
FRONT NEUROSCI-SWITZ. 2014; 8:
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Patellofemoral osteoarthritis after Insall"s proximal realignment for recurrent patellar dislocation.
Schüttler, KF; Struewer, J; Roessler, PP; Gesslein, M; Rominger, MB; Ziring, E; Efe, T;
Knee Surg Sports Traumatol Arthrosc. 2014; 22(11):2623-2628
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Role of Rho/ROCK signaling in the interaction of melanoma cells with the blood-brain barrier
Wilhelm, I; Fazakas, C; Molnar, J; Hasko, J; Vegh, AG; Cervenak, L; Nagyoszi, P; Nyul-Toth, A; Farkas, AE; Bauer, H; Guillemin, GJ; Bauer, HC; Varo, G; Krizbai, IA
PIGM CELL MELANOMA R. 2014; 27(1): 11-23.
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[18F]-fluoro-ethyl-L-tyrosine PET: a valuable diagnostic tool in neuro-oncology, but not all that glitters is glioma.
Hutterer, M; Nowosielski, M; Putzer, D; Jansen, NL; Seiz, M; Schocke, M; McCoy, M; Göbel, G; la Fougère, C; Virgolini, IJ; Trinka, E; Jacobs, AH; Stockhammer, G;
Neuro Oncol. 2013; 15(3):341-351
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Brain pericyte plasticity as a potential drug target in CNS repair.
Lange, S; Trost, A; Tempfer, H; Bauer, HC; Bauer, H; Rohde, E; Reitsamer, HA; Franklin, RJ; Aigner, L; Rivera, FJ;
Drug Discov Today. 2013; 18(9-10):456-463
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Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis
Vilela, MC; Lima, GK; Rodrigues, DH; Lacerda-Queiroz, N; Pedroso, VSP; Miranda, AS; Rachid, MA; Kroon, EG; Campos, MA; Teixeira, MM; Sellner, J; Teixeira, AL
BMC NEUROSCI. 2013; 14: 19
Originalarbeiten (Zeitschrift)
Serum from interferon-beta-1b-treated patients with early multiple sclerosis stabilizes the blood-brain barrier in vitro
Muller, M; Frese, A; Nassenstein, I; Hoppen, M; Marziniak, M; Ringelstein, EB; Kim, KS; Schabitz, WR; Kraus, J
MULT SCLER J. 2012; 18(2): 236-239.
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Oxidative stress and blood-brain barrier dysfunction under particular consideration of matrix metalloproteinases.
Lehner, C; Gehwolf, R; Tempfer, H; Krizbai, I; Hennig, B; Bauer, HC; Bauer, H;
Antioxid Redox Signal. 2011; 15(5):1305-1323
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Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign.
Sellner, J; Patel, A; Dassan, P; Brown, MM; Petzold, A;
NEUROCHEM RES. 2011; 36(12): 2287-2291.
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Impact of ABCC2 genotype on antiepileptic drug response in Caucasian patients with childhood epilepsy
Ufer, M; von Stulpnagel, C; Muhle, H; Haenisch, S; Remmler, C; Majed, A; Plischke, H; Stephani, U; Kluger, G; Cascorbi, I
PHARMACOGENET GENOM. 2011; 21(10): 624-630.
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Interferon-beta stabilizes barrier characteristics of the blood-brain barrier in four different species in vitro.
Kraus, J; Voigt, K; Schuller, AM; Scholz, M; Kim, KS; Schilling, M; Schäbitz, WR; Oschmann, P; Engelhardt, B;
MULT SCLER. 2008; 14(6): 843-852.
Originalarbeiten (Zeitschrift)
Hyperosmotic stress induces Axl activation and cleavage in cerebral endothelial cells.
Wilhelm, I; Nagyoszi, P; Farkas, AE; Couraud, PO; Romero, IA; Weksler, B; Fazakas, C; Dung, NT; Bottka, S; Bauer, H; Bauer, HC; Krizbai, IA;
J Neurochem. 2008; 107(1): 11-26.
Originalarbeiten (Zeitschrift)
Characterization of hepatic and brain metabolism in young adults with glycogen storage disease type 1: a magnetic resonance spectroscopy study.
Weghuber, D; Mandl, M; Krssak, M; Roden, M; Nowotny, P; Brehm, A; Krebs, M; Widhalm, K; Bischof, MG
Am J Physiol Endocrinol Metab. 2007; 293(5):E1378-E1384
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In bacterial meningitis cortical brain damage is associated with changes in parenchymal MMP-9/TIMP-1 ratio and increased collagen type IV degradation.
Sellner, J; Leib, SL;
Neurobiol Dis. 2006; 21(3): 647-656.
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Herpes-simplex virus encephalitis is characterized by an early MMP-9 increase and collagen type IV degradation.
Sellner, J; Simon, F; Meyding-Lamade, U; Leib, SL;
Brain Res. 2006; 1125(1):155-162
Originalarbeiten (Zeitschrift)
Protein S-100B--a prognostic marker for cerebral damage.
Stroick, M; Fatar, M; Ragoschke-Schumm, A; Fassbender, K; Bertsch, T; Hennerici, MG
Curr Med Chem. 2006; 13(25):3053-3060
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ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier.
Bronger, H; König, J; Kopplow, K; Steiner, HH; Ahmadi, R; Herold-Mende, C; Keppler, D; Nies, AT;
Cancer Res. 2005; 65(24): 11419-11428.
Originalarbeiten (Zeitschrift)
Hyperosmotic mannitol induces Src kinase-dependent phosphorylation of beta-catenin in cerebral endothelial cells.
Farkas, A; Szatmári, E; Orbók, A; Wilhelm, I; Wejksza, K; Nagyoszi, P; Hutamekalin, P; Bauer, H; Bauer, HC; Traweger, A; Krizbai, IA;
J Neurosci Res. 2005; 80(6): 855-861.
Originalarbeiten (Zeitschrift)
In search of the astrocytic factor(s) modulating blood-brain barrier functions in brain capillary endothelial cells in vitro.
Haseloff, RF; Blasig, IE; Bauer, HC; Bauer, H;
Cell Mol Neurobiol. 2005; 25(1): 25-39.
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Effect of oxidative stress on the junctional proteins of cultured cerebral endothelial cells.
Krizbai, IA; Bauer, H; Bresgen, N; Eckl, PM; Farkas, A; Szatmári, E; Traweger, A; Wejksza, K; Bauer, HC;
Cell Mol Neurobiol. 2005; 25(1): 12-39.
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Blood-brain barrier changes during compensated and decompensated hemorrhagic shock.
Krizbai, IA; Lenzser, G; Szatmari, E; Farkas, AE; Wilhelm, I; Fekete, Z; Erdos, B; Bauer, H; Bauer, HC; Sandor, P; Komjati, K;
Shock. 2005; 24(5): 428-433.
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Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts
Hamm, S; Dehouck, B; Kraus, J; Wolburg-Buchholz, K; Wolburg, H; Risau, W; Cecchelli, R; Engelhardt, B; Dehouck, MP
CELL TISSUE RES. 2004; 315(2): 157-166.
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Interferon-beta(1b) leads to a short-term increase of soluble but long-term stabilisation of cell surface bound adhesion molecules in multiple sclerosis
Kraus, J; Bauer, R; Chatzimanolis, N; Engelhardt, B; Tofighi, J; Bregenzer, T; Kuehne, BS; Stolz, E; Blaes, F; Morgen, K; Traupe, H; Kaps, M; Oschmann, P
J NEUROL. 2004; 251(4): 464-472.
Originalarbeiten (Zeitschrift)
High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs
Lutjohann, D; Stroick, M; Bertsch, T; Kuhl, S; Lindenthal, B; Thelen, K; Andersson, U; Bjorkhem, I; von Bergmann, K; Fassbender, K
STEROIDS. 2004; 69(6): 431-438.
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Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain.
Nies, AT; Jedlitschky, G; König, J; Herold-Mende, C; Steiner, HH; Schmitt, HP; Keppler, D;
Neuroscience. 2004; 129(2): 349-360.
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Microvessel density is not crucial for scintigraphic visualization of brain tumors using Tc-99m-MIBI
Staudenherz, A; Wolfsberger, S; Killer, M; Nasel, C; Puig, S; Marosi, C; Leitha, T; Hainfellner, JA
MICROVASC RES. 2004; 67(3): 218-222.
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Oxidative stress in cultured cerebral endothelial cells induces chromosomal aberrations, micronuclei, and apoptosis.
Bresgen, N; Karlhuber, G; Krizbai, I; Bauer, H; Bauer, HC; Eckl, PM;
J Neurosci Res. 2003; 72(3): 327-333.
Originalarbeiten (Zeitschrift)
HIV-Tat protein induces oxidative and inflammatory pathways in brain endothelium.
Toborek, M; Lee, YW; Pu, H; Malecki, A; Flora, G; Garrido, R; Hennig, B; Bauer, HC; Nath, A;
J Neurochem. 2003; 84(1): 169-179.
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Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme.
Wolburg, H; Wolburg-Buchholz, K; Kraus, J; Rascher-Eggstein, G; Liebner, S; Hamm, S; Duffner, F; Grote, EH; Risau, W; Engelhardt, B;
Acta Neuropathol. 2003; 105(6):586-592
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Neural induction of the blood-brain barrier: still an enigma.
Bauer, HC; Bauer, H;
Cell Mol Neurobiol. 2000; 20(1):13-28
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Does (99m)Tc-Sestamibi in high-grade malignant brain tumors reflect blood-brain barrier damage only?
Staudenherz, A; Fazeny, B; Marosi, C; Nasel, C; Hoffmann, M; Puig, S; Killer, M; Leitha, T;
Neuroimage. 2000; 12(1): 109-111.
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Ontogenic expression of the erythroid-type glucose transporter (Glut 1) in the telencephalon of the mouse: correlation to the tightening of the blood-brain barrier.
Bauer, H; Sonnleitner, U; Lametschwandtner, A; Steiner, M; Adam, H; Bauer, HC;
Brain Res Dev Brain Res. 1995; 86(1-2):317-325
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ECGF and heparin determine differentiation of cloned cerebral endothelial cells in vitro.
Amberger, A; Lemkin, PF; Sonderegger, P; Bauer, HC;
Mol Chem Neuropathol. 1993; 20(1): 33-43.
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Neovascularization and the appearance of morphological characteristics of the blood-brain barrier in the embryonic mouse central nervous system.
Bauer, HC; Bauer, H; Lametschwandtner, A; Amberger, A; Ruiz, P; Steiner, M;
Brain Res Dev Brain Res. 1993; 75(2): 269-278.
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Embryonic development of the CNS microvasculature in the mouse: new insights into the structural mechanisms of early angiogenesis.
Bauer, HC; Steiner, M; Bauer, H;
EXS. 1992; 61:64-68
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Diagnosis and treatment of deep cerebral vein thrombosis.
Erbguth, F; Brenner, P; Schuierer, G; Druschky, KF; Neundörfer, B;
Neurosurg Rev. 1991; 14(2):145-148
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Glial cells and neurons induce blood-brain barrier related enzymes in cultured cerebral endothelial cells.
Tontsch, U; Bauer, HC;
Brain Res. 1991; 539(2):247-253
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