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Forschungsdatenbank PMU-SQQUID


Gewähltes Keyword: TGF-beta

SMAD7 deficiency stimulates Müller progenitor cell proliferation during the development of the mammalian retina.
Kugler, M; Schlecht, A; Fuchshofer, R; Schmitt, SI; Kleiter, I; Aigner, L; Tamm, ER; Braunger, BM
HISTOCHEM CELL BIOL. 2017; 148(1): 21-32.
Originalarbeiten (Zeitschrift)
The TgF-beta system as a Potential Pathogenic Player in Disease Modulation of amyotrophic lateral sclerosis
Peters, S; Zitzelsperger, E; Kuespert, S; Iberl, S; Heydn, R; Johannesen, S; Petri, S; Aigner, L; Thal, DR; Hermann, A; Weishaupt, JH; Bruun, TH; Bogdahn, U
FRONT NEUROL. 2017; 8: 669
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Heterozygous modulation of TGF-β signaling does not influence Müller glia cell reactivity or proliferation following NMDA-induced damage.
Kugler, M; Schlecht, A; Fuchshofer, R; Kleiter, I; Aigner, L; Tamm, ER; Braunger, BM
HISTOCHEM CELL BIOL. 2015; 144(5): 443-455.
Originalarbeiten (Zeitschrift)
Impaired TGF-beta induced growth inhibition contributes to the increased proliferation rate of neural stem cells harboring mutant p53
Kumar, P; Naumann, U; Aigner, L; Wischhusen, J; Beier, CP; Beier, D
AM J CANCER RES. 2015; 5(11): 3436-3445.
Originalarbeiten (Zeitschrift)
Darbepoetin inhibits proliferation of hepatic cancer cells in the presence of TGF-β.
Ehnert, S; Freude, T; Eicher, C; Burkhardt, B; Martínez Sánchez, JJ; Neumann, J; Mühl-Benninghaus, R; Dooley, S; Pscherer, S; Nussler, AK;
Arch Toxicol. 2014; 88(1): 89-96.
Originalarbeiten (Zeitschrift)
[Use of Bone Morphogenetic Proteins (BMPs) for the Treatment of Pseudarthroses - Efficiency and Therapy Failure].
Hausmann, M; Ehnert, S; Hofmann, V; Döbele, S; Freude, T; Stöckle, U; Nussler, A;
Z Orthop Unfall. 2014; 152(2): 144-151.
Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis.
Marschallinger, J; Krampert, M; Couillard-Despres, S; Heuchel, R; Bogdahn, U; Aigner, L;
Exp Gerontol. 2014; 57: 149-154.
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Chronic CCl4 intoxication causes liver and bone damage similar to the human pathology of hepatic osteodystrophy: a mouse model to analyse the liver-bone axis.
Nussler, AK; Wildemann, B; Freude, T; Litzka, C; Soldo, P; Friess, H; Hammad, S; Hengstler, JG; Braun, KF; Trak-Smayra, V; Godoy, P; Ehnert, S;
Arch Toxicol. 2014; 88(4): 997-1006.
Originalarbeiten (Zeitschrift)
Anti-diabetic treatment regulates pro-fibrotic TGF-β serum levels in type 2 diabetics.
Pscherer, S; Freude, T; Forst, T; Nussler, AK; Braun, KF; Ehnert, S;
Diabetol Metab Syndr. 2013; 5(1):48
Originalarbeiten (Zeitschrift)
Current status of therapeutic targeting of developmental signalling pathways in oncology.
Kiesslich, T; Berr, F; Alinger, B; Kemmerling, R; Pichler, M; Ocker, M; Neureiter, D;
Curr Pharm Biotechnol. 2012; 13(11):2184-2220
Mechanical stimulation of the pro-angiogenic capacity of human fracture haematoma: involvement of VEGF mechano-regulation.
Groothuis, A; Duda, GN; Wilson, CJ; Thompson, MS; Hunter, MR; Simon, P; Bail, HJ; van Scherpenzeel, KM; Kasper, G;
Bone. 2010; 47(2): 438-444.
Originalarbeiten (Zeitschrift)
Matrix-independent stimulation of human tubular epithelial cell migration by Rho kinase inhibitors.
Kroening, S; Stix, J; Keller, C; Streiff, C; Goppelt-Struebe, M
J Cell Physiol. 2010; 223(3):703-712
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Insight into the molecular pathophysiology of delayed bone healing in a sheep model.
Lienau, J; Schmidt-Bleek, K; Peters, A; Weber, H; Bail, HJ; Duda, GN; Perka, C; Schell, H;
Tissue Eng Part A. 2010; 16(1): 191-199.
Originalarbeiten (Zeitschrift)
[Distribution planning of injured persons in mass disasters or catastrophes. Structuring of hospital capacities exemplified by the catastrophe network of the German Society for Trauma Surgery (DGU)].
Bail, HJ; Kleber, C; Haas, NP; Fischer, P; Mahlke, L; Matthes, G; Ruchholtz, S; Weidringer, JW;
Unfallchirurg. 2009; 112(10): 870-877.
Originalarbeiten (Zeitschrift)
[Fast track in casualty surgery].
Bail, HJ; Möbius, B; Haas, NP;
Chirurg. 2009; 80(8): 702-705.
[Emergencies in pediatric traumatology--fractures in the growing age and pediatric polytrauma].
Degenhardt, P; Kleber, C; Bail, HJ;
Anasthesiol Intensivmed Notfallmed Schmerzther. 2009; 44(6): 445-449.
Distraction osteogenesis enhances remodeling of remote bones of the skeleton: a pilot study.
Funk, JF; Krummrey, G; Perka, C; Raschke, MJ; Bail, HJ;
Clin Orthop Relat Res. 2009; 467(12): 3199-3205.
Originalarbeiten (Zeitschrift)
Humeral head necrosis rate at mid-term follow-up after open reduction and angular stable plate fixation for proximal humeral fractures.
Greiner, S; Kääb, MJ; Haas, NP; Bail, HJ;
Injury. 2009; 40(2): 186-191.
Originalarbeiten (Zeitschrift)
Differential regulation of blood vessel formation between standard and delayed bone healing.
Lienau, J; Schmidt-Bleek, K; Peters, A; Haschke, F; Duda, GN; Perka, C; Bail, HJ; Schütze, N; Jakob, F; Schell, H;
J Orthop Res. 2009; 27(9): 1133-1140.
Originalarbeiten (Zeitschrift)
Locally applied osteogenic predifferentiated progenitor cells are more effective than undifferentiated mesenchymal stem cells in the treatment of delayed bone healing.
Peters, A; Toben, D; Lienau, J; Schell, H; Bail, HJ; Matziolis, G; Duda, GN; Kaspar, K;
Tissue Eng Part A. 2009; 15(10): 2947-2954.
Originalarbeiten (Zeitschrift)
Osteochondral lesions of the talus: retrograde drilling with high-field-strength MR guidance.
Seebauer, CJ; Bail, HJ; Wichlas, F; Jung, T; Papanikolaou, IS; van der Voort, I; Rump, JC; Schilling, R; Winkelmann, A; Walther, T; Chopra, SS; Teichgräber, UK;
Radiology. 2009; 252(3): 857-864.
Originalarbeiten (Zeitschrift)
Tibia fracture following removal of the ETN (Expert Tibia Nail): a case report.
Seebauer, CJ; van Scherpenzeel, KM; Haas, NP; Bail, HJ;
Arch Orthop Trauma Surg. 2009; 129(7): 949-953.
Neoangiogenesis after combined transplantation of skeletal myoblasts and angiopoietic progenitors leads to increased cell engraftment and lower apoptosis rates in ischemic heart failure.
Bonaros, N; Rauf, R; Werner, E; Schlechta, B; Rohde, E; Kocher, A; Bonatti, J; Laufer, G;
Interact Cardiovasc Thorac Surg. 2008; 7(2):249-255
Originalarbeiten (Zeitschrift)
[Myocardial infarction as cause of an accident. The role of multislice CT in polytrauma management, differential diagnosis and insurance aspects].
Kleber, C; Oswald, B; Bail, HJ; Haas, NP; Kandziora, F;
Unfallchirurg. 2008; 111(12): 1026-1032.
The effect of TGF-beta2 on elastin, type VI collagen, and components of the proteolytic degradation system in human optic nerve astrocytes.
Neumann, C; Yu, A; Welge-Lüssen, U; Lütjen-Drecoll, E; Birke, M;
Invest Ophthalmol Vis Sci. 2008; 49(4):1464-1472
Originalarbeiten (Zeitschrift)
Mechanical induction of critically delayed bone healing in sheep: radiological and biomechanical results.
Schell, H; Thompson, MS; Bail, HJ; Hoffmann, JE; Schill, A; Duda, GN; Lienau, J;
J Biomech. 2008; 41(14): 3066-3072.
Originalarbeiten (Zeitschrift)
Expression and putative functions of GDF-15, a member of the TGF-beta superfamily, in human glioma and glioblastoma cell lines.
Strelau, J; Schmeer, C; Peterziel, H; Sackmann, T; Herold-Mende, C; Steiner, H; Weller, M; Unsicker, K;
Cancer Lett. 2008; 270(1): 30-39.
Originalarbeiten (Zeitschrift)
Autonomic renal denervation ameliorates experimental glomerulonephritis.
Veelken, R; Vogel, EM; Hilgers, K; Amann, K; Hartner, A; Sass, G; Neuhuber, W; Tiegs, G;
J Am Soc Nephrol. 2008; 19(7):1371-1378
Originalarbeiten (Zeitschrift)
Oxidative stress and TGF-beta2 increase heat shock protein 27 expression in human optic nerve head astrocytes.
Yu, AL; Fuchshofer, R; Birke, M; Kampik, A; Bloemendal, H; Welge-Lüssen, U;
Invest Ophthalmol Vis Sci. 2008; 49(12):5403-5411
Originalarbeiten (Zeitschrift)
Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis.
Kleiter, I; Pedré, X; Mueller, AM; Poeschl, P; Couillard-Despres, S; Spruss, T; Bogdahn, U; Giegerich, G; Steinbrecher, A;
J Neuroimmunol. 2007; 187(1-2):61-73
Originalarbeiten (Zeitschrift)
Functional role of bone morphogenetic protein-4 in isolated canine parietal cells.
Nitsche, H; Ramamoorthy, S; Sareban, M; Pausawasdi, N; Todisco, A;
Am J Physiol Gastrointest Liver Physiol. 2007; 293(3): G607-G614.
Originalarbeiten (Zeitschrift)
Hypoxia/reoxygenation and TGF-beta increase alphaB-crystallin expression in human optic nerve head astrocytes.
Yu, AL; Fuchshofer, R; Birke, M; Priglinger, SG; Eibl, KH; Kampik, A; Bloemendal, H; Welge-Lussen, U;
Exp Eye Res. 2007; 84(4):694-706
Originalarbeiten (Zeitschrift)
Ultrastructural and biochemical evaluation of the porcine anterior chamber perfusion model.
Bachmann, B; Birke, M; Kook, D; Eichhorn, M; Lütjen-Drecoll, E;
Invest Ophthalmol Vis Sci. 2006; 47(5):2011-2020
Originalarbeiten (Zeitschrift)
Biochemical and morphological analysis of basement membrane component expression in corneoscleral and cribriform human trabecular meshwork cells.
Fuchshofer, R; Welge-Lüssen, U; Lütjen-Drecoll, E; Birke, M;
Invest Ophthalmol Vis Sci. 2006; 47(3):794-801
Originalarbeiten (Zeitschrift)
Inhibition of p38 mitogen-activated protein kinase attenuates left ventricular dysfunction by mediating pro-inflammatory cardiac cytokine levels in a mouse model of diabetes mellitus.
Westermann, D; Rutschow, S; Van Linthout, S; Linderer, A; Bücker-Gärtner, C; Sobirey, M; Riad, A; Pauschinger, M; Schultheiss, HP; Tschöpe, C;
Diabetologia. 2006; 49(10):2507-2513
Originalarbeiten (Zeitschrift)
Transforming growth factor-beta 2 modulated extracellular matrix component expression in cultured human optic nerve head astrocytes.
Fuchshofer, R; Birke, M; Welge-Lussen, U; Kook, D; Lütjen-Drecoll, E;
Invest Ophthalmol Vis Sci. 2005; 46(2): 568-578.
Originalarbeiten (Zeitschrift)
Carvedilol improves left ventricular function in murine coxsackievirus-induced acute myocarditis association with reduced myocardial interleukin-1beta and MMP-8 expression and a modulated immune response.
Pauschinger, M; Rutschow, S; Chandrasekharan, K; Westermann, D; Weitz, A; Peter Schwimmbeck, L; Zeichhardt, H; Poller, W; Noutsias, M; Li, J; Schultheiss, HP; Tschope, C;
Eur J Heart Fail. 2005; 7(4):444-452
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Increased adenine nucleotide translocator 1 in reactive astrocytes facilitates glutamate transport.
Buck, CR; Jurynec, MJ; Gupta, DK; Law, AK; Bilger, J; Wallace, DC; McKeon, RJ;
Exp Neurol. 2003; 181(2): 149-158.
Originalarbeiten (Zeitschrift)
Dynamic expression patterns of transforming growth factor-beta(2) and transforming growth factor-beta receptors in experimental glomerulonephritis.
Hartner, A; Hilgers, KF; Bitzer, M; Veelken, R; Schöcklmann, HO;
J Mol Med (Berl). 2003; 81(1):3-42
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Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations.
Gahr, S; Merger, M; Bollheimer, LC; Hammerschmied, CG; Schölmerich, J; Hügl, SR;
J Mol Endocrinol. 2002; 28(2): 99-110.
Originalarbeiten (Zeitschrift)
Low doses of 2,3,7,8-tetrachlorodibenzo- p-dioxin increase transforming growth factor beta and cause myocardial fibrosis in marmosets ( Callithrix jacchus).
Riecke, K; Grimm, D; Shakibaei, M; Kossmehl, P; Schulze-Tanzil, G; Paul, M; Stahlmann, R;
Arch Toxicol. 2002; 76(5-6): 360-366.
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Growth factor-induced morphological, physiological and molecular characteristics in cerebral endothelial cells.
Krizbai, IA; Bauer, H; Amberger, A; Hennig, B; Szabó, H; Fuchs, R; Bauer, HC;
Eur J Cell Biol. 2000; 79(9):594-600
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Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy.
Lang, F; Klingel, K; Wagner, CA; Stegen, C; Warntges, S; Friedrich, B; Lanzendorfer, M; Melzig, J; Moschen, I; Steuer, S; Waldegger, S; Sauter, M; Paulmichl, M; Gerke, V; Risler, T; Gamba, G; Capasso, G; Kandolf, R; Hebert, SC; Massry, SG; Broër, S;
Proc Natl Acad Sci U S A. 2000; 97(14): 8157-8162.
Originalarbeiten (Zeitschrift)
Dilated cardiomyopathy is associated with significant changes in collagen type I/III ratio.
Pauschinger, M; Knopf, D; Petschauer, S; Doerner, A; Poller, W; Schwimmbeck, PL; Kühl, U; Schultheiss, HP;
Circulation. 1999; 99(21): 2750-2756.
Originalarbeiten (Zeitschrift)