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Forschungsdatenbank PMU-SQQUID


Gewähltes Keyword: CYP

Early inhibition of endothelial retinoid uptake upon myocardial infarction restores cardiac function and prevents cell, tissue, and animal death.
Danzl, K; Messner, B; Doppler, C; Nebert, C; Abfalterer, A; Sakic, A; Temml, V; Heinz, K; Streitwieser, R; Edelmann, T; Mairhofer, M; Grimm, M; Laufer, G; Zierer, A; Stuppner, H; Schuster, D; Ploner, C; Müller, T; Bernhard, D;
J Mol Cell Cardiol. 2019; 126:105-117
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Performance of the AsperGenius® PCR assay for detecting azole resistant Aspergillus fumigatus in BAL fluids from allogeneic HSCT recipients: A prospective cohort study from Essen, West Germany.
Pelzer, BW; Seufert, R; Koldehoff, M; Liebregts, T; Schmidt, D; Buer, J; Rath, PM; Steinmann, J;
Med Mycol. 2019;
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Azole Resistance in Aspergillus fumigatus in Patients with Cystic Fibrosis: A Matter of Concern?
Hamprecht, A; Morio, F; Bader, O; Le Pape, P; Steinmann, J; Dannaoui, E;
Mycopathologia. 2018; 183(1):151-160
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[Subconjunctival minimally invasive glaucoma surgery : Methods and clinical results].
Lenzhofer, M; Hohensinn, M; Strohmaier, C; Reitsamer, HA
OPHTHALMOLOGE. 2018; 115(5): 381-387.
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Impact of Scyphozoan Venoms on Human Health and Current First Aid Options for Stings.
Remigante, A; Costa, R; Morabito, R; La Spada, G; Marino, A; Dossena, S
TOXINS. 2018; 10(4):
Prevalence and characterization of azole-resistant Aspergillus fumigatus in patients with cystic fibrosis: a prospective multicentre study in Germany.
Seufert, R; Sedlacek, L; Kahl, B; Hogardt, M; Hamprecht, A; Haase, G; Gunzer, F; Haas, A; Grauling-Halama, S; MacKenzie, CR; Essig, A; Stehling, F; Sutharsan, S; Dittmer, S; Killengray, D; Schmidt, D; Eskandarian, N; Steinmann, E; Buer, J; Hagen, F; Meis, JF; Rath, PM; Steinmann, J;
J Antimicrob Chemother. 2018; 73(8): 2047-2053.
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FunResDB-A web resource for genotypic susceptibility testing of Aspergillus fumigatus.
Weber, M; Schaer, J; Walther, G; Kaerger, K; Steinmann, J; Rath, PM; Spiess, B; Buchheidt, D; Hamprecht, A; Kurzai, O;
Med Mycol. 2018; 56(1): 117-120.
A Model for Phylogenetic Chemosystematics: Evolutionary History of Quinones in the Scent Gland Secretions of Harvestmen.
Raspotnig, G; Schaider, M; Föttinger, P; Schönhofer, A;
Front Ecol Evol. 2017; 5: 139
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Allele Drop Out Conferred by a Frequent CYP2D6 Genetic Variation For Commonly Used CYP2D6*3 Genotyping Assays.
Scantamburlo, G; Tziolia, K; Zopf, M; Bernardinelli, E; Soyal, SM; Civello, DA; Vanoni, S; Dossena, S; Patsch, W; Patrinos, GP; Paulmichl, M; Nofziger, C;
Cell Physiol Biochem. 2017; 43(6): 2297-2309.
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Investigation of mechanisms of bendiocarb resistance in Anopheles gambiae populations from the city of Yaoundé, Cameroon.
Antonio-Nkondjio, C; Poupardin, R; Tene, BF; Kopya, E; Costantini, C; Awono-Ambene, P; Wondji, CS;
Malar J. 2016; 15(1): 424
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Supraciliary Micro-stent Implantation for Open-Angle Glaucoma Failing Topical Therapy: 1-Year Results of a Multicenter Study.
García-Feijoo, J; Rau, M; Grisanti, S; Grisanti, S; Höh, H; Erb, C; Guguchkova, P; Ahmed, I; Grabner, G; Reitsamer, H; Shaarawy, T; Ianchulev, T;
Am J Ophthalmol. 2015; 159(6):1075-1081.e1
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CYP39A1 polymorphism is associated with toxicity during intensive induction chemotherapy in patients with advanced head and neck cancer.
Melchardt, T; Hufnagl, C; Magnes, T; Weiss, L; Hutarew, G; Neureiter, D; Schlattau, A; Moser, G; Gaggl, A; Tränkenschuh, W; Greil, R; Egle, A;
BMC Cancer. 2015; 15:725
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Pectate lyase pollen allergens: sensitization profiles and cross-reactivity pattern.
Pichler, U; Hauser, M; Wolf, M; Bernardi, ML; Gadermaier, G; Weiss, R; Ebner, C; Yokoi, H; Takai, T; Didierlaurent, A; Rafaiani, C; Briza, P; Mari, A; Behrendt, H; Wallner, M; Ferreira, F;
PLoS One. 2015; 10(5):e0120038
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Comparative analysis of response to selection with three insecticides in the dengue mosquito Aedes aegypti using mRNA sequencing.
David, JP; Faucon, F; Chandor-Proust, A; Poupardin, R; Riaz, MA; Bonin, A; Navratil, V; Reynaud, S;
BMC Genomics. 2014; 15:174
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Molecular characterization of DDT resistance in Anopheles gambiae from Benin.
Djègbè, I; Agossa, FR; Jones, CM; Poupardin, R; Cornelie, S; Akogbéto, M; Ranson, H; Corbel, V;
Parasit Vectors. 2014; 7:409
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CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae.
Edi, CV; Djogbénou, L; Jenkins, AM; Regna, K; Muskavitch, MA; Poupardin, R; Jones, CM; Essandoh, J; Kétoh, GK; Paine, MJ; Koudou, BG; Donnelly, MJ; Ranson, H; Weetman, D;
PLoS Genet. 2014; 10(3):e1004236
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Heavy metals affect nematocysts discharge response and biological activity of crude venom in the jellyfish Pelagia noctiluca (Cnidaria, Scyphozoa).
Morabito, R; Dossena, S; La Spada, G; Marino, A
Cell Physiol Biochem. 2014; 34(2):244-254
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Chronic CCl4 intoxication causes liver and bone damage similar to the human pathology of hepatic osteodystrophy: a mouse model to analyse the liver-bone axis.
Nussler, AK; Wildemann, B; Freude, T; Litzka, C; Soldo, P; Friess, H; Hammad, S; Hengstler, JG; Braun, KF; Trak-Smayra, V; Godoy, P; Ehnert, S;
Arch Toxicol. 2014; 88(4): 997-1006.
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CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations.
Province, MA; Goetz, MP; Brauch, H; Flockhart, DA; Hebert, JM; Whaley, R; Suman, VJ; Schroth, W; Winter, S; Zembutsu, H; Mushiroda, T; Newman, WG; Lee, MT; Ambrosone, CB; Beckmann, MW; Choi, JY; Dieudonné, AS; Fasching, PA; Ferraldeschi, R; Gong, L; Haschke-Becher, E; Howell, A; Jordan, LB; Hamann, U; Kiyotani, K; Krippl, P; Lambrechts, D; Latif, A; Langsenlehner, U; Lorizio, W; Neven, P; Nguyen, AT; Park, BW; Purdie, CA; Quinlan, P; Renner, W; Schmidt, M; Schwab, M; Shin, JG; Stingl, JC; Wegman, P; Wingren, S; Wu, AH; Ziv, E; Zirpoli, G; Thompson, AM; Jordan, VC; Nakamura, Y; Altman, RB; Ames, MM; Weinshilboum, RM; Eichelbaum, M; Ingle, JN; Klein, TE;
Clin Pharmacol Ther. 2014; 95(2):216-227
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Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis.
Bechmann, LP; Kocabayoglu, P; Sowa, JP; Sydor, S; Best, J; Schlattjan, M; Beilfuss, A; Schmitt, J; Hannivoort, RA; Rust, C; Berr, F; Tschopp, O; Gerken, G; Friedman, SL; Geier, A; Canbay, A;
Hepatology. 2013; 57(4): 139-406.
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The central role of mosquito cytochrome P450 CYP6Zs in insecticide detoxification revealed by functional expression and structural modelling.
Chandor-Proust, A; Bibby, J; Régent-Kloeckner, M; Roux, J; Guittard-Crilat, E; Poupardin, R; Riaz, MA; Paine, M; Dauphin-Villemant, C; Reynaud, S; David, JP;
Biochem J. 2013; 455(1):7-85
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Dissecting the mechanisms responsible for the multiple insecticide resistance phenotype in Anopheles gambiae s.s., M form, from Vallée du Kou, Burkina Faso.
Kwiatkowska, RM; Platt, N; Poupardin, R; Irving, H; Dabire, RK; Mitchell, S; Jones, CM; Diabaté, A; Ranson, H; Wondji, CS;
Gene. 2013; 519(1):98-106
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Mitochondrial hyperpolarization in pulmonary vascular remodeling. Mitochondrial uncoupling protein deficiency as disease model.
Pak, O; Sommer, N; Hoeres, T; Bakr, A; Waisbrod, S; Sydykov, A; Haag, D; Esfandiary, A; Kojonazarov, B; Veit, F; Fuchs, B; Weisel, FC; Hecker, M; Schermuly, RT; Grimminger, F; Ghofrani, HA; Seeger, W; Weissmann, N;
Am J Respir Cell Mol Biol. 2013; 49(3): 358-367.
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A randomized trial of genotype-guided dosing of warfarin.
Pirmohamed, M; Burnside, G; Eriksson, N; Jorgensen, AL; Toh, CH; Nicholson, T; Kesteven, P; Christersson, C; Wahlström, B; Stafberg, C; Zhang, JE; Leathart, JB; Kohnke, H; Maitland-van der Zee, AH; Williamson, PR; Daly, AK; Avery, P; Kamali, F; Wadelius, M;
N Engl J Med. 2013; 369(24): 2294-2303.
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Molecular mechanisms associated with increased tolerance to the neonicotinoid insecticide imidacloprid in the dengue vector Aedes aegypti.
Riaz, MA; Chandor-Proust, A; Dauphin-Villemant, C; Poupardin, R; Jones, CM; Strode, C; Régent-Kloeckner, M; David, JP; Reynaud, S;
Aquat Toxicol. 2013; 126:326-337
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A randomized trial of genotype-guided dosing of acenocoumarol and phenprocoumon.
Verhoef, TI; Ragia, G; de Boer, A; Barallon, R; Kolovou, G; Kolovou, V; Konstantinides, S; Le Cessie, S; Maltezos, E; van der Meer, FJ; Redekop, WK; Remkes, M; Rosendaal, FR; van Schie, RM; Tavridou, A; Tziakas, D; Wadelius, M; Manolopoulos, VG; Maitland-van der Zee, AH;
N Engl J Med. 2013; 369(24): 2304-2312.
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Cost-effectiveness of pharmacogenetic-guided dosing of phenprocoumon in atrial fibrillation.
Verhoef, TI; Redekop, WK; Veenstra, DL; Thariani, R; Beltman, PA; van Schie, RM; de Boer, A; Maitland-van der Zee, AH;
Pharmacogenomics. 2013; 14(8): 869-883.
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Gene amplification, ABC transporters and cytochrome P450s: unraveling the molecular basis of pyrethroid resistance in the dengue vector, Aedes aegypti.
Bariami, V; Jones, CM; Poupardin, R; Vontas, J; Ranson, H;
PLoS Negl Trop Dis. 2012; 6(6):e1692
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An evaluation of gene-gene interaction between the CYP2C9 and VKORC1 genotypes affecting the anticoagulant effect of phenprocoumon and acenocoumarol.
van Schie, RM; Babajeff, AM; Schalekamp, T; Wessels, JA; le Cessie, S; de Boer, A; van der Meer, FJ; van Meegen, E; Verhoef, TI; Rosendaal, FR; Maitland-van der Zee, AH;
J Thromb Haemost. 2012; 10(5):767-772
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Long-term anticoagulant effects of the CYP2C9 and VKORC1 genotypes in acenocoumarol users.
Verhoef, TI; Redekop, WK; Buikema, MM; Schalekamp, T; Van Der Meer, FJ; Le Cessie, S; Wessels, JA; Van Schie, RM; De Boer, A; Teichert, M; Visser, LE; Maitland-Van Der Zee, AH;
J Thromb Haemost. 2012; 10(4): 606-614.
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A proposal for an individualized pharmacogenetics-based warfarin initiation dose regimen for patients commencing anticoagulation therapy.
Avery, PJ; Jorgensen, A; Hamberg, AK; Wadelius, M; Pirmohamed, M; Kamali, F;
Clin Pharmacol Ther. 2011; 90(5): 701-706.
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Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data.
van Schie, RM; Wessels, JA; le Cessie, S; de Boer, A; Schalekamp, T; van der Meer, FJ; Verhoef, TI; van Meegen, E; Rosendaal, FR; Maitland-van der Zee, AH;
Eur Heart J. 2011; 32(15): 1909-1917.
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Impact of CYP2C8 and 2C9 polymorphisms on coronary artery disease and myocardial infarction in the LURIC cohort.
Haschke-Becher, E; Kirchheiner, J; Trummer, O; Grünbacher, G; Kainz, A; Boehm, BO; März, W; Renner, W;
Pharmacogenomics. 2010; 11(10): 1359-1365.
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Transcription profiling of eleven cytochrome P450s potentially involved in xenobiotic metabolism in the mosquito Aedes aegypti.
Poupardin, R; Riaz, MA; Vontas, J; David, JP; Reynaud, S;
Insect Mol Biol. 2010; 19(2):185-193
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Impact of CYP2D6*4 genotype on progression free survival in tamoxifen breast cancer treatment.
Stingl, JC; Parmar, S; Huber-Wechselberger, A; Kainz, A; Renner, W; Seeringer, A; Brockmöller, J; Langsenlehner, U; Krippl, P; Haschke-Becher, E;
Curr Med Res Opin. 2010; 26(11):2535-2542
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A systematic review of cost-effectiveness analyses of pharmacogenetic-guided dosing in treatment with coumarin derivatives.
Verhoef, TI; Redekop, WK; Darba, J; Geitona, M; Hughes, DA; Siebert, U; de Boer, A; Maitland-van der Zee, AH; Barallon, R; Briz, M; Daly, A; Haschke-Becher, E; Kamali, F; Kirchheiner, J; Manolopoulos, VG; Pirmohamed, M; Rosendaal, FR; van Schie, RM; Wadelius, M;
Pharmacogenomics. 2010; 11(7): 989-1002.
Olanzapine and breast-feeding: changes of plasma concentrations of olanzapine in a breast-fed infant over a period of 5 months
Whitworth, A; Stuppaeck, C; Yazdi, K; Kralovec, K; Geretsegger, C; Zernig, G; Aichhorn, W
J PSYCHOPHARMACOL. 2010; 24(1): 121-123.
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Genotype-guided dosing of coumarin derivatives: the European pharmacogenetics of anticoagulant therapy (EU-PACT) trial design.
van Schie, RM; Wadelius, MI; Kamali, F; Daly, AK; Manolopoulos, VG; de Boer, A; Barallon, R; Verhoef, TI; Kirchheiner, J; Haschke-Becher, E; Briz, M; Rosendaal, FR; Redekop, WK; Pirmohamed, M; Maitland van der Zee, AH;
PHARMACOGENOMICS. 2009; 10(10): 1687-1695.
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Cross-induction of detoxification genes by environmental xenobiotics and insecticides in the mosquito Aedes aegypti: impact on larval tolerance to chemical insecticides.
Poupardin, R; Reynaud, S; Strode, C; Ranson, H; Vontas, J; David, JP;
Insect Biochem Mol Biol. 2008; 38(5):540-551
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MyoD and Myogenin expression during myogenic phases in brown trout: a precocious onset of mosaic hyperplasia is a prerequisite for fast somatic growth.
Steinbacher, P; Haslett, JR; Obermayer, A; Marschallinger, J; Bauer, HC; Sänger, AM; Stoiber, W;
Dev Dyn. 2007; 236(4):1106-1114
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The immunomodulatory effects of the dimer of lysozyme (KLP-602) in carp (Cyprinus carpio L)--in vivo study.
Rymuszka, A; Studnicka, M; Siwicki, AK; Sierosławska, A; Bownik, A;
Ecotoxicol Environ Saf. 2005; 61(1):121-127
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The identification of ligand features essential for PXR activation by pharmacophore modeling.
Schuster, D; Langer, T
J Chem Inf Model. 2005; 45(2):431-439
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Experimental hepatic uroporphyria induced by the diphenyl-ether herbicide fomesafen in male DBA/2 mice.
Krijt, J; Psenák, O; Vokurka, M; Chlumská, A; Fakan, F;
Toxicol Appl Pharmacol. 2003; 189(1):2-38
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Controlled trial with a monthly combination injectable contraceptive in Europe.
Brucker, C;
Gynecol Endocrinol. 2001; 15 Suppl 3: 11-14.
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In vivo effect of the organophosphorus insecticide trichlorphon on immune response of carp (Cyprinus carpio). II. Effect of high doses of trichlorphon on nonspecific immune response.
Siwicki, AK; Cossarini-Dunier, M; Studnicka, M; Demael, A;
Ecotoxicol Environ Saf. 1990; 19(1):99-105
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