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Research Database PMU-SQQUID

CH domains revisited.
Stradal, T; Kranewitter, W; Winder, SJ; Gimona, M;
FEBS Lett. 1998; 431(2): 134-137.
Kurzberichte/Notes

PMU-Authors

Gimona Mario

Abstract

A sequence motif of about 100 amino acids, termed the xxxcalponin homology domainxxx has been suggested to confer actin binding to a variety of cytoskeletal and signalling molecules, Here we analyse and compare the sequences of all calponin homology domain-containing proteins identified to date. We propose that single calponin homology domains do not confer actin-binding per se and that the actin-binding motifs of crosslinking proteins, which comprise two disparate calponin homology domains, represent a unique protein module, (C) 1998 Federation of European Biochemical Societies.


Useful keywords (using NLM MeSH Indexing)

Actins/metabolism*

Amino Acid Sequence

Animals

Calcium-Binding Proteins/chemistry*

Calcium-Binding Proteins/metabolism

Databases, Factual

Humans

Microfilament Proteins

Molecular Sequence Data

Phylogeny

Protein Conformation

Sequence Homology, Amino Acid


Find related publications in this database (Keywords)

calponin
calponin homology domain
actin binding