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Research Database PMU-SQQUID

Association of lower urinary tract symptoms and chronic ischaemia of the lower urinary tract in elderly women and men: assessment using colour Doppler ultrasonography.
Pinggera, GM; Mitterberger, M; Steiner, E; Pallwein, L; Frauscher, F; Aigner, F; Bartsch, G; Strasser, H;
BJU Int. 2008; 102(4):470-474
Originalarbeiten (Zeitschrift)


Mitterberger Michael


OBJECTIVES To investigate. using transrectal colour Doppler ultrasonography, (TRCDUS) whether perfusion of the bladder and prostate is reduced in elderly patients with lower urinary tract symptoms (LUTS), common in later life, as experimental data suggest that chronic ischaemia has a key role in the development of LUTS. PATIENTS, SUBJECTS AND METHODS In 32 elderly patients with 1 (12 women, mean age 82.3 years, group 1; and 20 men, 79.4 years, group 2) perfusion of the bladder neck (in women) and of the bladder neck and prostate (in men) was measured using TRCDUS and the resistive index (I and colour pixel density (Cl determined, assessed by a TRUS unit and special software. To assess the age-related effect two control groups of 10 young healthy women (mean age 42.3 years. group 3) and 10 age-matched healthy men (mean age 41.5 years, group 4) were also enrolled. RESULTS Irrespective of gender, there was markedly lower bladder perfusion in elderly patients with LUTS than in the younger subjects. The mean (SD) RI of the bladder neck in group 1, of 0.88 (0.06), and group 2, of 0.80 (0.08), was higher than in control groups 3. of 0.62 (0.05) and group 4, of 0.64 (0.09). The results were similar for the CPD measurements. The frequency of daily and nightly micturition showed a strong negative correlation with perfusion in the urinary bladder. CONCLUSION In elderly patients with I there was decreased perfusion of the bladder neck and prostate when assessed using TRCDUS. Therefore, decreased perfusion in the urinary bladder might be responsible for the development of LUTS with advancing age.

Useful keywords (using NLM MeSH Indexing)

Age Factors


Aged, 80 and over

Case-Control Studies

Chronic Disease







Prostate/blood supply*






Quality of Life

Ultrasonography, Doppler, Color*

Urinary Bladder/blood supply

Urinary Bladder/pathology

Urinary Bladder/ultrasonography

Urinary Tract/blood supply*

Urinary Tract/pathology

Urinary Tract/ultrasonography

Urination Disorders/etiology*

Urination Disorders/pathology

Urination Disorders/ultrasonography

Find related publications in this database (Keywords)

blood perfusion
resistive index