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Research Database PMU-SQQUID

Long-term results of split-thickness skin grafting with and without additional dermal matrix in severe traumatic soft tissue defects of the lower limb.
Wallner, B; Öhlbauer, M; von Rüden, C;
Eur J Trauma Emerg Surg. 2023; 49(1):551-557
Full papers/articles (Journal)


von Rüden Christian


Aim of this study was to compare the use of split-thickness skin graft (STSG) with and without additional MatriDerm
This retrospective study included patients treated in a European level I trauma center between June 2013 and July 2018 in terms of a severe traumatic soft tissue defect of the lower extremity using STSG alone or in combination with the acellular dermal substitute MatriDerm
A total of 147 cases were included in this study. The overall healing rate (number of patients with take rate ≥ 75%) was 88/147 (60%) and did not demonstrate significant differences between the treatment groups (p = 0.15). Despite the difference in wound complexity between the treatment groups, there was no difference regarding the scar tissue quality 12 months postoperatively. In about 25% of all cases, a post-operative event was mentioned that had to be revised surgically.
Surgical treatment with STSG and additional MatriDerm

Useful keywords (using NLM MeSH Indexing)


Skin Transplantation*


Retrospective Studies

Wound Healing

Lower Extremity/surgery