Research Database PMU-SQQUID

Evaluating a Targeted Cancer Therapy Approach Mediated by RNA trans-Splicing In Vitro and in a Xenograft Model for Epidermolysis Bullosa-Associated Skin Cancer
Woess, K; Sun, Y; Morio, H; Stierschneider, A; Kaufmann, A; Hainzl, S; Trattner, L; Kocher, T; Tockner, B; Leb-Reichl, V; Steiner, M; Brachtl, G; South, AP; Bauer, JW; Reichelt, J; Furihata, T; Wally, V; Koller, U; Piñón Hofbauer, J; Guttmann-Gruber, C;
Int J Mol Sci. 2022; 23(1):
Full papers/articles (Journal)

Abstract/Keywords Web of Science PubMed Full Text

PMU-Authors

Bauer Johann
Brachtl Gabriele
Guttmann-Gruber Christina
Hainzl Stefan
Kaufmann Anna
Kocher Thomas
Koller Ulrich
Pinon Hofbauer Josefina
Reichelt Julia
Reichl Victoria
Steiner Markus
Tockner Birgit
Trattner Lisa
Wally Verena

Abstract

Conventional anti-cancer therapies based on chemo- and/or radiotherapy represent highly effective means to kill cancer cells but lack tumor specificity and, therefore, result in a wide range of iatrogenic effects. A promising approach to overcome this obstacle is spliceosome-mediated RNA

Find related publications in this database (Keywords)

epidermolysis bullosa
squamous cell carcinoma
cancer gene therapy
spliceosome mediated RNA trans-splicing
herpes simplex virus thymidine kinase
ganciclovir