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Research Database PMU-SQQUID

[Epilepsy in the aged : Challenges in diagnostics and treatment].
Rohracher, A; Trinka, E
Z Gerontol Geriatr. 2021; 54(4):395-408
Full papers/articles (Journal)


Astner-Rohracher Alexandra
Trinka Eugen


Epilepsy is the third most frequent neurological disorder in aged patients after stroke and dementia. The incidence of epilepsy increases with age with the highest rates in patients >= 65 years old. Due to demographic changes the number of aged patients with epilepsy is expected to increase further in the coming years. The leading cause of new onset epilepsy in aged patients is cerebrovascular disease followed by dementia. The recognition of seizures in aged patients is often delayed. Status epilepticus occurs more frequently in aged patients and is associated with a high mortality and morbidity. Antiepileptic drug (AED) treatment of aged patients is complicated by comorbidities and polypharmacy and AEDs with a low interaction profile and high tolerability should be selected. Levetiracetam and lamotrigine are the AEDs of choice due to low interactions and good tolerability.

Useful keywords (using NLM MeSH Indexing)


Anticonvulsants/therapeutic use

Carbamazepine*/therapeutic use


Epilepsy*/drug therapy



Lamotrigine/therapeutic use

Levetiracetam/therapeutic use

Find related publications in this database (Keywords)

Status epilepticus
Antiepileptic drugs