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Research Database PMU-SQQUID

Sample sizes and statistical methods in interventional studies on individuals with spinal cord injury: A systematic review.
Zimmermann, G; Bolter, LM; Sluka, R; Höller, Y; Bathke, AC; Thomschewski, A; Leis, S; Lattanzi, S; Brigo, F; Trinka, E;
J Evid Based Med. 2019; 12(3):-208.
Full papers/articles (Journal)

PMU-Authors

Höller Yvonne
Leis Stefan
Thomschewski Aljoscha
Trinka Eugen
Zimmermann Georg Johannes

Abstract

Prevalence and incidence of spinal cord injury (SCI) are low. However, sample sizes have not been systematically examined yet, although this might represent useful information for study planning and power considerations. Therefore, our objective was to determine the median sample size in clinical trials on SCI individuals. Moreover, within small-sample size studies, statistical methods and awareness of potential problems regarding small samples were examined.


Find related publications in this database (Keywords)

effect size
power
rare disease
spinal cord trauma
statistical data analysis