Research Database PMU-SQQUID

Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state
Villa, A; Klein, B; Janssen, B; Pedragosa, J; Pepe, G; Zinnhardt, B; Vugts, DJ; Gelosa, P; Sironi, L; Beaino, W; Damont, A; Dolle, F; Jego, B; Winkeler, A; Ory, D; Solin, O; Vercouillie, J; Funke, U; Laner-Plamberger, S; Blomster, LV; Christophersen, P; Vegeto, E; Aigner, L; Jacobs, A; Planas, AM; Maggi, A; Windhorst, AD
THERANOSTICS. 2018; 8(19): 5400-5418.
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Abstract/Keywords Web of Science PubMed PUBMED Central Full Text

PMU-Authors

Aigner Ludwig
Klein Barbara
Laner-Plamberger Sandra

Abstract

Microglia are potential targets for therapeutic intervention in neurological and neurodegenerative diseases affecting the central nervous system. In order to assess the efficacy of therapies aimed to reduce the tissue damaging activities of microglia and/or to promote the protective potential of these cells, suitable pre-clinical and clinical tools for the

Find related publications in this database (Keywords)

neuroinflammation
microglia
translational markers
radiochemistry
PET tracers