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Research Database PMU-SQQUID

Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles
Reiner, AT; Witwer, KW; van Balkom, BWM; de Beer, J; Brodie, C; Corteling, RL; Gabrielsson, S; Gimona, M; Ibrahim, AG; de Kleijn, D; Lai, CP; Lotvall, J; del Portillo, HA; Reischl, IG; Riazifar, M; Salomon, C; Tahara, H; Toh, WS; Wauben, MHM; Yang, VK; Yang, YJ; Yeo, RWY; Yin, H; Giebel, B; Rohde, E; Lim, SK
STEM CELL TRANSL MED. 2017; 6(8):
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PMU-Authors

Gimona Mario
Rohde Eva

Abstract

Growing interest in extracellular vesicles (EVs, including exosomes and microvesicles) as therapeutic entities, particularly in stem cell-related approaches, has underlined the need for standardization and coordination of development efforts. Members of the International Society for Extracellular Vesicles and the Society for Clinical Research and Translation of Extracellular Vesicles Singapore convened a Workshop on this topic to discuss the opportunities and challenges associated with development of EV-based therapeutics at the preclinical and clinical levels. This review outlines topic-specific action items that, if addressed, will enhance the development of best-practice models for EV therapies.


Find related publications in this database (Keywords)

Stem cells
Cellular therapy
Clinical trials
Clinical translation
Extracellular vesicles
Therapeutics
Exosomes
Microvesicles