PMU-Authors
Egle AlexanderAbstract
Hereditary hemorrhagic telangiectasia is an inherited autosomal dominant disease presenting with recurrent bleeding episodes and iron deficiency anemia due to vascular malformations. Hereditary hemorrhagic telangiectasia is associated with an increased risk of stroke, gastrointestinal bleeding and pulmonary hypertension and life expectancy is significantly reduced. Excess vascular endothelial growth factor (VEGF) plays a key role in the pathophysiology of the disease.
Useful keywords (using NLM MeSH Indexing)
Angiogenesis Inhibitors/administration*
dosage
Bevacizumab/administration*
dosage*
Dose-Response Relationship, Drug
Drug Administration Schedule
Epistaxis/diagnosis
Epistaxis/etiology
Epistaxis/prevention*
control*
Humans
Telangiectasia, Hereditary Hemorrhagic/complications
Telangiectasia, Hereditary Hemorrhagic/diagnosis*
Telangiectasia, Hereditary Hemorrhagic/drug therapy*
Treatment Outcome
Vascular Endothelial Growth Factor A/antagonists*
inhibitors
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