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Research Database PMU-SQQUID

Temporo-parietal junction activity in theory-of-mind tasks: falseness, beliefs, or attention.
Aichhorn, M; Perner, J; Weiss, B; Kronbichler, M; Staffen, W; Ladurner, G;
J COGNITIVE NEUROSCI. 2009; 21(6): 117-192.
Originalarbeiten (Zeitschrift)

PMU-Authors

Kronbichler Martin
Staffen Wolfgang

Abstract

By combining the false belief (FB) and photo (PH) vignettes to identify theory-of-mind areas with the false sign (FS) vignettes, we re-establish the functional asymmetry between the left and right temporo-parietal junction (TPJ). The right TPJ (TPJ-R) is specially sensitive to processing belief information, whereas the left TPJ (TPJ-L) is equally responsible for FBs as well as FSs. Measuring BOLD at two time points in each vignette, at the time the FB-inducing information (or lack of information) is presented and at the time the test question is processed, made clear that the FB is processed spontaneously as soon as the relevant information is presented and not on demand for answering the question in contrast to extant behavioral data. Finally, a fourth, true belief vignette (TB) required teleological reasoning, that is, prediction of a rational action without any doubts being raised about the adequacy of the actorxxxs information about reality. Activation by this vignette supported claims that the TPJ-R is activated by TBs as well as FBs.


Useful keywords (using NLM MeSH Indexing)

Adult

Analysis of Variance

Attention*

Brain Mapping*

Confidence Intervals

Culture*

Drug Combinations

Female

Functional Laterality/physiology*

Humans

Image Processing, Computer-Assisted/methods

Magnetic Resonance Imaging/methods

Male

Neural Pathways/physiology*

Neuropsychological Tests

Parietal Lobe/physiology

Peroxides/blood

Reality Testing*

Temporal Lobe/physiology

Time Factors

Urea/analogs*

derivatives

Urea/blood

Young Adult