PMU-Autor/inn/en
Rohde EvaAbstract
Regenerative stem cell therapy (SCT) is currently being tested in clinical trials. The ideal type and source of cells have not yet been defined. Lineage (Lin) depletion is an experimental procedure capable of enriching all recently recognized SC types with regenerative potency. This study was performed to define a practicable monoclonal antibody (MoAb) cocktail for Lin depletion and to test whether clinical-scale Lin depletion is possible.
Useful keywords (using NLM MeSH Indexing)
Adult
Antibodies, Monoclonal/immunology*
Biomarkers
Cell Lineage/immunology*
Cell Separation/methods
Female
Flow Cytometry/methods*
Fluorescent Antibody Technique
Hematopoietic Stem Cell Transplantation*
Hematopoietic Stem Cells/cytology*
Hematopoietic Stem Cells/immunology
Humans
Immunophenotyping
Leukapheresis/methods
Male
Membrane Proteins/immunology
Middle Aged