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Forschungsdatenbank PMU-SQQUID

Excitability of the motor cortex to magnetic stimulation in patients with cerebellar lesions.
DILAZZARO, V; RESTUCCIA, D; MOLINARI, M; LEGGIO, MG; NARDONE, R; FOGLI, D; TONALI, P
J Neurol Neurosurg Psychiatry. 1994; 57(1):108-110
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Nardone Raffaele

Abstract

The excitability of the motor cortex to magnetic stimulation was evaluated in seven patients with cerebellar lesions (six patients with a unilateral lesion) and in 20 control subjects. Magnetic motor threshold was defined at rest. In all but one of the patients with a hemicerebellar lesion the threshold was higher in the motor cortex contralateral to the impaired hemicerebellum and the right/left threshold asymmetry was clearly greater than normal. In the patient with a lesion involving both cerebellar hemispheres the magnetic threshold was above the normal limit on both sides. The latencies of motor responses were normal in all patients. This increase in the magnetic threshold of the motor cortex functionally related to the impaired hemicerebellum suggests the existence of a facilitating tonic action of the cerebellum on central motor circuits that might act at the cortical, or spinal level, or both.


Useful keywords (using NLM MeSH Indexing)

Adult

Aged

Cerebellar Diseases/diagnosis*

Cerebellar Diseases/physiopathology

Cerebellum/physiopathology*

Female

Humans

Magnetics*

Male

Middle Aged

Motor Cortex/physiology*

Neural Pathways/physiology