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Forschungsdatenbank PMU-SQQUID

Isolated oculomotor nerve palsy as the presenting clinical manifestation of a meningeal carcinomatosis: a case report.
Nardone, R; Herz, M; Egarter-Vigl, E; Tezzon, F
NEUROL SCI. 2006; 27(4): 288-290.


Nardone Raffaele


We present a previously unreported case of isolated oculomotor nerve palsy as the inaugural clinical sign of meningeal carcinomatosis (MC). Gadolinium-enhanced magnetic resonance images (MRI) were unremarkable. Cerebrospinal fluid (CSF) analysis showed malignant cells consistent with a pulmonary adenocarcinoma; the chest CT revealed a small pulmonary mass in the upper right lobe. This case highlights the importance of considering MC in all patients who develop sudden oculomotor palsy; lumbar punctures should always be performed on patients with normal MRI when other possible causes of oculomotor palsy have been ruled out.

Useful keywords (using NLM MeSH Indexing)

Carcinoma/cerebrospinal fluid




Magnetic Resonance Imaging/methods


Meningeal Neoplasms/cerebrospinal fluid

Meningeal Neoplasms/complications*

Meningeal Neoplasms/diagnosis

Middle Aged

Oculomotor Nerve Diseases/cerebrospinal fluid

Oculomotor Nerve Diseases/diagnosis

Oculomotor Nerve Diseases/etiology*

Tomography, X-Ray Computed/methods

Find related publications in this database (Keywords)

meningeal carcinomatosis
lung adenocarcinoma
oculomotor nerve
magnetic resonance imaging
cerebrospinal fluid analysis