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Forschungsdatenbank PMU-SQQUID

Historical vignette: medical treatment of status epilepticus.
Janz, D
Epilepsia. 2013; 54 Suppl 6:3-10


Trinka Eugen


The treatment of status epilepticus has changed over the past five decades since the first colloquium on status epilepticus, held in Marseille in 1962. New intravenous drugs, such as valproate, levetiracetam, lacosomide or ketamine and new routes of administration, such as intranasal or bucal, as well as high-class randomized clinical trials in the prehospital setting and early stages of status have changed the field. However it is remarkable, how the basic principles and difficulties of treatment of status epilepticus have remained the same. This article is as a translation of a narrative review authored by Dieter Janz at the Marseille Colloquium 1962, published in 1967. The medical practice and all available treatment at that time have been reviewed critically in the article. The translation of the original French article has been kept as close as possible to the original, to give a detailed account on the treatment of status at that time.

Useful keywords (using NLM MeSH Indexing)



Anticonvulsants/therapeutic use*

History, 19th Century

History, 20th Century


Infusions, Intravenous

Seizures/drug therapy

Status Epilepticus/drug therapy

Status Epilepticus/history*

Treatment Outcome

Find related publications in this database (Keywords)

Status epilepticus
Marseille Colloquium 1962
medical treatment