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Forschungsdatenbank PMU-SQQUID

Tissue Effects Resulting from Eraser Laser Enucleation of the Prostate: In vivo Investigation.
Lusuardi, L; Hager, M; Kloss, B; Hruby, S; Colleselli, D; Zimmermann, R; Janetschek, G; Mitterberger, M;
Urol Int. 2013; 91(4): 391-396.
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Colleselli Daniela
Hager Martina
Hruby Stephan
Janetschek Günter
Kloss Birgit
Lusuardi Lukas
Mitterberger Michael

Abstract

Background/Aims/Objectives: To describe the depth of the laser coagulation zone in vivo based on histological examinations and the functional outcome of a 1,318-nm diode laser for enucleation in benign prostatic enlargement (BPE). Methods: A total of 20 patients with BPE were treated by laser Eraser® enucleation of the prostate (ELEP). Prostatic tissue wedges were evaluated to assess the depth of the ELEP coagulation zones. Additionally, patients were assessed preoperatively and 12 months postoperatively. Results: The coagulation zones were 0.36 ± 0.17 mm in epithelial tissue, 0.28 ± 0.15 mm in stromal tissue, and 0.25 ± 0.12 mm in mixed tissue. The coagulation area at the cutting edge completely sealed capillary vessels, reaching a depth of 0.35 ± 0.15 mm. The diameter of the coagulated vessels measured 1.75 ± 0.83 mm. Mean blood loss was 115.54 ± 93.12 ml, catheter time 1.35 ± 0.33 days, and hospital stay 1.89 ± 0.52 days. The International Prostate Symptom Score, maximal flow rate, and quality of life significantly improved 12 months after the procedure. Conclusions: ELEP is safe and effective for BPE treatment and yields good results at a follow-up of 1 year. Because of the limited penetration depth, damage to the urinary sphincter is not expected. © 2013 S. Karger AG, Basel.


Find related publications in this database (Keywords)

Prostate Benign prostatic enlargement
Laser surgery
Diode laser