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Forschungsdatenbank PMU-SQQUID

One 10-core prostate biopsy is superior to two sets of sextant prostate biopsies.
Fink, KG; Hutarew, G; Pytel, A; Esterbauer, B; Jungwirth, A; Dietze, O; Schmeller, NT;
BJU INT. 2003; 92(4): 385-388.
Originalarbeiten (Zeitschrift)


Dietze Otto
Hutarew Georg


To compare the efficiency of different transrectal ultrasonography (TRUS)-guided prostate biopsy techniques for detecting prostate cancer. In all, 81 prostates from radical prostatectomy were used and two consecutive sets of sextant biopsies and one 10-core biopsy taken in each specimen. The 10-core biopsy consisted of a sextant biopsy and four cores from the far lateral areas of the prostate. To simulate a transrectal biopsy procedure, all biopsies were taken under TRUS guidance. In the first set of sextant biopsies 44 prostate cancers (54%) were detected and in the second set 51 (63%). Combining both sets of sextant biopsies 57 (70%) of the carcinomas were detected. One set of 10-core biopsies detected 66 (82%) of all prostate cancers. Overall, with the 10-core biopsies 16% more prostate tumours were diagnosed than with two consecutive sets of sextant biopsies. To find the same number of prostate cancers as with the 10-core technique, 14% of patients undergoing sextant biopsy would require a second set and 11% at least a third set of biopsies. The 10-core prostate biopsy technique is superior to the commonly used sextant technique and could spare patients unnecessary repeated biopsy. Even after including a second set of sextant biopsies, the total detection rate with these 12 biopsies was inferior to the 10-core technique.

Useful keywords (using NLM MeSH Indexing)

Biopsy, Needle/methods

Biopsy, Needle/standards*





Prostatic Neoplasms/pathology*

Prostatic Neoplasms/surgery

Sensitivity and Specificity

Ultrasonography, Interventional

Find related publications in this database (Keywords)

prostate cancer
prostate biopsy