Forschungsdatenbank PMU-SQQUID

PMU-Autor/inn/en

Abstract

A 24 year old woman in the 33rd week of pregnancy developed progressive neurological complications with right sided hemiparesis in association with the occurrence of linear scleroderma "en coup de sabre" (LSCS) and preexisting plaque-morphea, already being treated by balneophototherapy. Further progression of neurological symptoms led to a caesarean section with the delivery of a healthy child. Brain magnetic resonance imaging (MRI) showed focal T2 signal increases in the left frontoparietal region directly adjacent to the area of LSCS. Cerebrospinal fluid analysis revealed oligoclonal bands, suggesting an intracerebral inflammatory process. Subsequent pulsed corticosteroid treatment led to a remission of neurological symptoms and to a marked resolution of the MRI lesions.

Useful keywords (using NLM MeSH Indexing)

Adult

Female

Humans

Magnetic Resonance Imaging

Methylprednisolone/administration*

dosage

Methylprednisolone/therapeutic use*

Nervous System Diseases/diagnosis*

Nervous System Diseases/drug therapy*

Nervous System Diseases/etiology

Neuroprotective Agents/administration*

dosage

Neuroprotective Agents/therapeutic use*

Pregnancy

Pregnancy Complications/diagnosis*

Pregnancy Complications/drug therapy*

Pulse Therapy, Drug

Scleroderma, Localized/complications

Scleroderma, Localized/diagnosis*

Scleroderma, Localized/drug therapy*

Tomography, X-Ray Computed