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Forschungsdatenbank PMU-SQQUID

Linear scleroderma "en coup de sabre" coexisting with plaque-morphea: neuroradiological manifestation and response to corticosteroids.
Unterberger, I; Trinka, E; Engelhardt, K; Muigg, A; Eller, P; Wagner, M; Sepp, N; Bauer, G;
J Neurol Neurosurg Psychiatry. 2003; 74(5): 661-664.


Trinka Eugen


A 24 year old woman in the 33rd week of pregnancy developed progressive neurological complications with right sided hemiparesis in association with the occurrence of linear scleroderma "en coup de sabre" (LSCS) and preexisting plaque-morphea, already being treated by balneophototherapy. Further progression of neurological symptoms led to a caesarean section with the delivery of a healthy child. Brain magnetic resonance imaging (MRI) showed focal T2 signal increases in the left frontoparietal region directly adjacent to the area of LSCS. Cerebrospinal fluid analysis revealed oligoclonal bands, suggesting an intracerebral inflammatory process. Subsequent pulsed corticosteroid treatment led to a remission of neurological symptoms and to a marked resolution of the MRI lesions.

Useful keywords (using NLM MeSH Indexing)




Magnetic Resonance Imaging



Methylprednisolone/therapeutic use*

Nervous System Diseases/diagnosis*

Nervous System Diseases/drug therapy*

Nervous System Diseases/etiology

Neuroprotective Agents/administration*


Neuroprotective Agents/therapeutic use*


Pregnancy Complications/diagnosis*

Pregnancy Complications/drug therapy*

Pulse Therapy, Drug

Scleroderma, Localized/complications

Scleroderma, Localized/diagnosis*

Scleroderma, Localized/drug therapy*

Tomography, X-Ray Computed