Forschungsdatenbank PMU-SQQUID

CXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation.
Kowarik, MC; Cepok, S; Sellner, J; Grummel, V; Weber, MS; Korn, T; Berthele, A; Hemmer, B;
J Neuroinflammation. 2012; 9 (93): 1-11.
Originalarbeiten (Zeitschrift)

Abstract/Keywords Web of Science PubMed PUBMED Central Full Text

PMU-Autor/inn/en

Sellner Johann

Abstract

The chemokines and cytokines CXCL13, CXCL12, CCL19, CCL21, BAFF and APRIL are believed to play a role in the recruitment of B cells to the central nervous system (CNS) compartment during neuroinflammation. To determine which chemokines/cytokines show the strongest association with a humoral immune response in the cerebrospinal fluid (CSF), we measured their concentrations in the CSF and correlated them with immune cell subsets and antibody levels.

Find related publications in this database (Keywords)

CCL19
CCL21
CXCL12
CXCL13
BAFF
APRIL
B cells and plasmablasts