The intercellular adhesion molecule-1 (ICAM-1) is a member of the Ig supergene family. ICAM-1 is expressed on various cells like peripheral blood lymphocytes, endothelial cells or thymic cells and the cell surface form is supposed to be shed into a soluble form. The expression of ICAM-1 is induced by cytokines like Interleukin-1, TNF alpha or interferon gamma. The aim of the study was to investigate whether changes of cell surface and soluble ICAM-1 in the cerebrospinal fluid (CSF) and blood are indicative for disease activity in patients with multiple sclerosis (MS).
Useful keywords (using NLM MeSH Indexing)
Intercellular Adhesion Molecule-1/blood
Intercellular Adhesion Molecule-1/cerebrospinal fluid
Intercellular Adhesion Molecule-1/metabolism*
Find related publications in this database (Keywords)cerebrospinal fluid