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Severe pediatric blunt trauma--successful ROTEM-guided hemostatic therapy with fibrinogen concentrate and no administration of fresh frozen plasma or platelets.
Ziegler, B; Schimke, C; Marchet, P; Stögermüller, B; Schöchl, H; Solomon, C;
Clin Appl Thromb Hemost. 2012; 19(4):453-459
Originalarbeiten (Zeitschrift)


Schimke Christa
Ziegler Bernhard


Use of allogeneic blood products to treat pediatric trauma may be challenged, particularly in relation to safety. We report successful treatment of a child with severe abdominal and pelvic injuries with preemptive fibrinogen supplementation followed by rotational thromboelastometry (ROTEM)-guided, goal-directed hemostatic therapy. Fibrinogen concentrate was administered (total dose: 2 g), while transfusion of fresh frozen plasma and platelet concentrate was avoided. Activated partial thromboplastin time was prolonged and Quick values were low but ROTEM clotting time values remained normal, therefore, no thrombin-generating drugs were considered necessary. This case shows the potential for hemostatic treatment with coagulation factor concentrates to be applied to pediatric trauma.

Find related publications in this database (Keywords)

fibrinogen concentrate (Haemocomplettan P
rotational thromboelastometry (ROTEM)