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Forschungsdatenbank PMU-SQQUID

Normalization of nomenclature for peptide motifs as ligands of modular protein domains.
Aasland, R; Abrams, C; Ampe, C; Ball, LJ; Bedford, MT; Cesareni, G; Gimona, M; Hurley, JH; Jarchau, T; Lehto, VP; Lemmon, MA; Linding, R; Mayer, BJ; Nagai, M; Sudol, M; Walter, U; Winder, SJ;
FEBS Lett. 2002; 513(1): 141-144.
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PMU-Autor/inn/en

Gimona Mario

Abstract

We propose a normalization of symbols and terms used to describe, accurately and succinctly, the detailed interactions between amino acid residues of pairs of interacting proteins at protein:protein (or protein: peptide) interfaces. Our aim is to unify several diverse descriptions currently in use in order to facilitate communication in the rapidly progressing field of signaling by protein domains. In order for the nomenclature to be convenient and widely used, we also suggest a parallel set of symbols restricted to the ASCII format allowing accurate parsing of the nomenclature to a computer-readable form. This proposal will be reviewed in the future and will therefore be open for the inclusion of new rules, modifications and changes. (C) 2002 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.


Useful keywords (using NLM MeSH Indexing)

Binding Sites

Ligands

Peptides/chemistry*

Peptides/classification

Protein Binding

Proteins/chemistry*

Proteins/metabolism

Terminology as Topic*

src Homology Domains


Find related publications in this database (Keywords)

protein-protein interaction
peptide motif
protein domain, specificity and recognition
proteomics
glossary
nomenclature
ASCII format