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Forschungsdatenbank PMU-SQQUID

Carotid artery stenting versus no stenting assisting thrombectomy for acute ischaemic stroke: protocol for a systematic review of randomised clinical trials with meta-analyses and trial sequential analyses.
Steglich-Arnholm, H; Holtmannspötter, M; Gluud, C; Krieger, DW;
Syst Rev. 2016; 5(1):208
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Holtmannspötter Markus

Abstract

In patients with intracranial large vessel arterial occlusion, ipsilateral extracranial carotid artery occlusions or near-occlusions pose a significant hurdle in endovascular management of acute ischaemic stroke. Stenting of the carotid lesion may be beneficial in this situation to provide a stable access for introducing catheters through the carotid lesion into the intracranial vasculature and the target occlusion. Furthermore, carotid stenting may ensure ample blood flow for wash-out of clot material and reperfusion of the ischaemic penumbral tissue. However, antiplatelet therapy administered to prevent stent thrombosis and sudden increase in blood flow after reopening of the carotid lesion may increase the risk for intracranial haemorrhagic complications. This review aims to assess the benefits and harms of carotid stenting vs. no stenting assisting thrombectomy for acute ischaemic stroke.


Useful keywords (using NLM MeSH Indexing)

Carotid Arteries*

Humans

Randomized Controlled Trials as Topic*

Stents/statistics*

numerical data*

Stroke/therapy*

Systematic Reviews as Topic

Thrombectomy*


Find related publications in this database (Keywords)

Stroke
Thrombectomy
Acute
Carotid
Carotid occlusion
Stenting