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Forschungsdatenbank PMU-SQQUID

Arriba: effects of an educational intervention on prescribing behaviour in prevention of CVD in general practice.
Keller, H; Krones, T; Becker, A; Hirsch, O; Sonnichsen, AC; Popert, U; Kaufmann-Kolle, P; Rochon, J; Wegscheider, K; Baum, E; Donner-Banzhoff, N
Eur J Prev Cardiol. 2012; 19(3):322-329
Originalarbeiten (Zeitschrift)


Sönnichsen Andreas


Evidence on the effectiveness of educational interventions on prescribing behaviour modification in prevention of cardiovascular disease is still insufficient. We evaluated the effects of a brief educational intervention on prescription of hydroxymethylglutaryl-CoA reductase inhibitors (statins), inhibitors of platelet aggregation (IPA), and antihypertensive agents (AH).
Cluster randomised controlled trial with continuous medical education (CME) groups of general practitioners (GPs).
Prescription of statins, IPA, and AH were verified prior to study start (BL), immediately after index consultation (IC), and at follow-up after 6 months (FU). Prescription in patients at high risk (>15% risk of a cardiovascular event in 10 years, based on the Framingham equation) and no prescription in low-risk patients (≤ 15%) were considered appropriate.
An intervention effect on prescribing could only be found for IPA. Generally, changes in prescription over time were all directed towards higher prescription rates and persisted to FU, independent of risk status and group allocation.
The active implementation of a brief evidence-based educational intervention on global risk in CVD did not lead directly to risk-adjusted changes in prescription. Investigations on an extended time scale would capture whether decision support of this kind would improve prescribing risk-adjusted sustainably.

Useful keywords (using NLM MeSH Indexing)


Antihypertensive Agents/therapeutic use

Attitude of Health Personnel*

Cardiovascular Agents/therapeutic use*

Cardiovascular Diseases/etiology

Cardiovascular Diseases/prevention*


Decision Support Techniques*

Drug Prescriptions

Education, Medical, Continuing*


General Practice*


Guideline Adherence

Health Knowledge, Attitudes, Practice*


Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use

Logistic Models


Middle Aged

Platelet Aggregation Inhibitors/therapeutic use

Practice Guidelines as Topic

Practice Patterns, Physicians"*

Preventive Health Services*

Risk Assessment

Risk Factors

Time Factors

Find related publications in this database (Keywords)

Antihypertensive agents
cardiovascular diseases
drug therapy
hydroxymethylglutaryl-CoA reductase inhibitors
primary health care