PMU-Autor/inn/en
Dossena SilviaAbstract
ICln is a multifunctional protein involved in the generation of chloride currents activated during regulatory volume decrease (RVD) after cell swelling (ICl(swell)). Growth factor receptors play a key role in different cellular processes and epidermal growth factor (EGF) regulates swelling-activated chloride permeability.
Useful keywords (using NLM MeSH Indexing)
Animals
Cell Size
Chloride Channels/genetics
Chloride Channels/metabolism
Chloride Channels/physiology*
Culture Media, Serum-Free/pharmacology
Epidermal Growth Factor/pharmacology*
Fluorescence Resonance Energy Transfer
Humans
Mice
NIH 3T3 Cells
Patch-Clamp Techniques
Proteins/genetics
Proteins/metabolism
Recombinant Fusion Proteins/genetics
Recombinant Fusion Proteins/metabolism
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EGF