In previous studies event-related potentials and oscillations in response to subjectxxxs own name have been analyzed extensively on group-level in healthy subjects and in patients with a disorder of consciousness. Subjectxxxs own name as a deviant produces a P3. With equiprobable stimuli, non-phase-locked alpha oscillations are smaller in response to subjectxxxs own name compared to other names or subjectxxxs own name backwards. However, little is known about replicability on a single-subject level. Seventeen healthy subjects were assessed in an own-name paradigm with equiprobable stimuli of subjectxxxs own name, another name, and subjectxxxs own name backwards. Event-related potentials and non-phase locked oscillations were analyzed with single-subject, non-parametric statistics. No consistent results were found either for ERPs or for the non-phase locked changes of oscillatory activities. Only 4 subjects showed a robust effect as expected, that is, a lower activity in the alpha-beta range to subjectxxxs own name compared to other conditions. Four subjects elicited a higher activity for subjectxxxs own name. Thus, analyzing the EEG reactivity in the own-name paradigm with equiprobable stimuli on a single-subject level yields a high variance between subjects. In future research, single-subject statistics should be applied for examining the validity of physiologic measurements in other paradigms and for examining the pattern of reactivity in patients. (C) 2011 Elsevier B.V. All rights reserved.
Useful keywords (using NLM MeSH Indexing)
Evoked Potentials, Auditory/physiology*
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