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Forschungsdatenbank PMU-SQQUID

Hsa-miR-375/RASD1 Signaling May Predict Local Control in Early Breast Cancer.
Zellinger, B; Bodenhofer, U; Engländer, IA; Kronberger, C; Strasser, P; Grambozov, B; Fastner, G; Stana, M; Reitsamer, R; Sotlar, K; Sedlmayer, F; Zehentmayr, F;
Genes (Basel). 2020; 11(12):
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Fastner Gerd
Grambozov Brane
Kronberger Cornelia
Reitsamer Roland
Sedlmayer Felix
Sotlar Karl
Stana Markus
Strasser Peter
Zehentmayr Franz
Zellinger Barbara

Abstract

In order to characterize the various subtypes of breast cancer more precisely and improve patients selection for breast conserving therapy (BCT), molecular profiling has gained importance over the past two decades. MicroRNAs, which are small non-coding RNAs, can potentially regulate numerous downstream target molecules and thereby interfere in carcinogenesis and treatment response via multiple pathways. The aim of the current two-phase study was to investigate whether hsa-miR-375-signaling through RASD1 could predict local control (LC) in early breast cancer.


Find related publications in this database (Keywords)

hsa-miR-375
RASD1
early stage breast cancer
local control
predictive markers