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Forschungsdatenbank PMU-SQQUID

Ipsilateral motor evoked potentials in a patient with unihemispheric cortical atrophy due to Rasmussen encephalitis.
Nardone, R; Langthaler, PB; Orioli, A; Versace, V; Scarano, GI; Brigo, F; Saltuari, L; Carnicelli, L; Trinka, E; Sebastianelli, L
NEURAL REGEN RES. 2019; 14(6): 1025-1028.
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Langthaler Patrick Benjamin
Nardone Raffaele
Trinka Eugen

Abstract

The role of the ipsilaterally descending motor pathways in the recovery mechanisms after unilateral hemispheric damage is still poorly understood. Motor output reorganization was investigated in a 56-year-old male patient with acquired unilateral hemispheric atrophy due to Rasmussen encephalitis. In particular, the ipsilateral corticospinal pathways were explored using focal transcranial magnetic stimulation. In the first dorsal interosseous and wrist extensors muscles, the median amplitudes of the ipsilateral motor evoked potentials induced by transcranial magnetic stimulation in the patient were higher than those of 10 age-matched healthy control subjects. In the biceps brachii muscle, the median amplitudes of the ipsilateral motor evoked potentials were the second largest in the patient compared to the controls. This study demonstrated a reinforcement of ipsilateral motor projections from the unaffected motor cortex to the hemiparetic hand in a subject with acquired unihemispheric cortical damage.


Find related publications in this database (Keywords)

transcranial magnetic stimulation
motor cortex
ipsilateral motor evoked potentials
ipsilateral motor pathways
Rasmussen encephalitis
cortical atrophy
hemispheric damage