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Forschungsdatenbank PMU-SQQUID

Topiramate, perampanel and brivaracetam in status epilepticus. How should they be used and what effect can be expected?
Rohracher, A; Kellinghaus, C; Strzelczyk, A
Z EPILEPTOL. 2018; 31(4): 256-261.
Originalarbeiten (Zeitschrift)


Rohracher Alexandra


Once benzodiazepines and intravenous anticonvulsants, such as phenytoin, valproate or levetiracetam fail in the first line treatment of status epilepticus, further anticonvulsants are used. This article describes the currently available data and publications on the use of two exclusively enteral anticonvulsants (topiramate and perampanel) and an enteral and parenteral anticonvulsant (brivaracetam) in status epilepticus. The pharmacological and clinical data on the use of these substances in status epilepticus are presented and recommendations are given for use in daily clinical practice.

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