Forschungsdatenbank PMU-SQQUID

T cell epitopes of the timothy grass pollen allergen Phl p 5 of mice and men and the detection of allergen-specific T cells using Class II Ultimers.
Stoecklinger, A; Scheiblhofer, S; Roesler, E; Lang, A; Fastner, G; Sedlmayer, F; Lang, R; Danzer, M; Thalhamer, J; Weiss, R;
Int Arch Allergy Immunol. 2012; 158(4): 326-334.
Originalarbeiten (Zeitschrift)

Abstract/Keywords Web of Science PubMed Full Text

PMU-Autor/inn/en

Fastner Gerd
Lang Roland
Sedlmayer Felix

Abstract

Knowledge of allergen-specific T cell epitopes is a prerequisite not only for therapeutic approaches but also for elucidating immunological mechanisms of type I allergy. Ex vivo detection of allergen-specific T cells using class II tetramer technology has become an important tool for investigating immune responses in atopic and healthy individuals.

Useful keywords (using NLM MeSH Indexing)

Amino Acid Sequence

Animals

Epitope Mapping

Epitopes, T-Lymphocyte/immunology*

Female

Humans

Immunodominant Epitopes/immunology

Immunoglobulin E/blood

Immunoglobulin E/immunology

Lymphocyte Activation/immunology

Mice

Mice, Inbred BALB C

Mice, Inbred C57BL

Molecular Sequence Data

Plant Proteins/immunology*

Staining and Labeling

T-Lymphocytes/immunology*

Find related publications in this database (Keywords)

Phl p 5
Epitope mapping
Tetramers
BALB/c mouse
C57BL/6 mouse