Forschungsdatenbank PMU-SQQUID

Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data.
Campbell, BCV; van Zwam, WH; Goyal, M; Menon, BK; Dippel, DWJ; Demchuk, AM; Bracard, S; White, P; Dávalos, A; Majoie, CBLM; van der Lugt, A; Ford, GA; de la Ossa, NP; Kelly, M; Bourcier, R; Donnan, GA; Roos, YBWEM; Bang, OY; Nogueira, RG; Devlin, TG; van den Berg, LA; Clarençon, F; Burns, P; Carpenter, J; Berkhemer, OA; Yavagal, DR; Pereira, VM; Ducrocq, X; Dixit, A; Quesada, H; Epstein, J; Davis, SM; Jansen, O; Rubiera, M; Urra, X; Micard, E; Lingsma, HF; Naggara, O; Brown, S; Guillemin, F; Muir, KW; van Oostenbrugge, RJ; Saver, JL; Jovin, TG; Hill, MD; Mitchell, PJ;
Lancet Neurol. 2018; 17(1):47-53
Originalarbeiten (Zeitschrift)

Abstract/Keywords Web of Science PubMed Full Text

PMU-Autor/inn/en

Holtmannspötter Markus
Jedlitschka Angela
Killer-Oberpfalzer Monika
Müller-Thies-Broussalis Erasmia
Mutzenbach Sebastian
Stadler Katharina
Weymayr Friedrich

Abstract

General anaesthesia (GA) during endovascular thrombectomy has been associated with worse patient outcomes in observational studies compared with patients treated without GA. We assessed functional outcome in ischaemic stroke patients with large vessel anterior circulation occlusion undergoing endovascular thrombectomy under GA, versus thrombectomy not under GA (with or without sedation) versus standard care (ie, no thrombectomy), stratified by the use of GA versus standard care.

Useful keywords (using NLM MeSH Indexing)

Aged

Aged, 80 and over

Anesthesia, General/methods*

Brain Ischemia/therapy*

Female

Humans

Male

Middle Aged

Outcome and Process Assessment, Health Care/statistics*

numerical data*

Randomized Controlled Trials as Topic/statistics*

numerical data*

Stroke/therapy*

Thrombectomy/methods*