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Forschungsdatenbank PMU-SQQUID

Insecticide resistance in the dengue vector Aedes aegypti from Martinique: distribution, mechanisms and relations with environmental factors.
Marcombe, S; Mathieu, RB; Pocquet, N; Riaz, MA; Poupardin, R; Sélior, S; Darriet, F; Reynaud, S; Yébakima, A; Corbel, V; David, JP; Chandre, F;
PLoS One. 2012; 7(2):e30989
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Poupardin Rodolphe

Abstract

87%). Real time quantitative RT-PCR showed the potential involvement of several candidate detoxification genes in insecticide resistance. Principal Component Analysis (PCA) performed with variables characterizing Ae. aegypti from Martinique permitted to underline potential links existing between resistance distribution and other variables such as agriculture practices, vector control interventions and urbanization. Insecticide resistance is widespread but not homogeneously distributed across Martinique. The influence of environmental and operational factors on the evolution of the resistance and mechanisms are discussed.


Useful keywords (using NLM MeSH Indexing)

Acetylcholinesterase/genetics

Acetylcholinesterase/metabolism

Aedes/drug effects

Aedes/enzymology*

Aedes/genetics

Aging/drug effects

Animals

Biological Assay

Cytochrome P-450 Enzyme System/genetics

Cytochrome P-450 Enzyme System/metabolism

Dengue/parasitology*

Environment*

Female

Gene Expression Regulation, Enzymologic/drug effects

Genes, Insect/genetics

Genetic Association Studies

Genotype

Geography

Insect Vectors/drug effects*

Insect Vectors/enzymology

Insect Vectors/genetics

Insecticide Resistance/drug effects*

Insecticide Resistance/genetics

Larva/drug effects

Larva/genetics

Martinique

Mutation/genetics

Nitriles/toxicity*

Phenotype

Population Dynamics

Principal Component Analysis

Pyrethrins/toxicity*

Reference Standards

Temefos/toxicity*

Transcription, Genetic/drug effects