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Forschungsdatenbank PMU-SQQUID

Temephos resistance in Aedes aegypti in Colombia compromises dengue vector control.
Grisales, N; Poupardin, R; Gomez, S; Fonseca-Gonzalez, I; Ranson, H; Lenhart, A;
PLoS Negl Trop Dis. 2013; 7(9):e2438
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Poupardin Rodolphe

Abstract

Control and prevention of dengue relies heavily on the application of insecticides to control dengue vector mosquitoes. In Colombia, application of the larvicide temephos to the aquatic breeding sites of Aedes aegypti is a key part of the dengue control strategy. Resistance to temephos was recently detected in the dengue-endemic city of Cucuta, leading to questions about its efficacy as a control tool. Here, we characterize the underlying mechanisms and estimate the operational impact of this resistance.


Useful keywords (using NLM MeSH Indexing)

Aedes/drug effects*

Animals

Biological Assay

Colombia/epidemiology

Dengue/epidemiology

Dengue/prevention*

control*

Dengue/transmission

Disease Vectors*

Drug Synergism

Gene Expression Profiling

Humans

Insect Control/methods*

Insecticide Resistance*

Insecticides/pharmacology*

Larva/drug effects

Microarray Analysis

Organothiophosphates/pharmacology

Temefos/pharmacology*