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Forschungsdatenbank PMU-SQQUID

Impact of agriculture on the selection of insecticide resistance in the malaria vector Anopheles gambiae: a multigenerational study in controlled conditions.
Nkya, TE; Poupardin, R; Laporte, F; Akhouayri, I; Mosha, F; Magesa, S; Kisinza, W; David, JP;
Parasit Vectors. 2014; 7:480
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Poupardin Rodolphe

Abstract

Resistance of mosquitoes to insecticides is mainly attributed to their adaptation to vector control interventions. Although pesticides used in agriculture have been frequently mentioned as an additional force driving the selection of resistance, only a few studies were dedicated to validate this hypothesis and characterise the underlying mechanisms. While insecticide resistance is rising dramatically in Africa, deciphering how agriculture affects resistance is crucial for improving resistance management strategies. In this context, the multigenerational effect of agricultural pollutants on the selection of insecticide resistance was examined in Anopheles gambiae.


Useful keywords (using NLM MeSH Indexing)

Agriculture

Animals

Anopheles/drug effects*

Dose-Response Relationship, Drug

Gene Expression Regulation

Genotype

Insect Vectors/drug effects*

Insect Vectors/parasitology

Insecticide Resistance/genetics*

Insecticides/administration*

dosage

Insecticides/pharmacology*

Malaria/transmission*

Protein Array Analysis

Reverse Transcriptase Polymerase Chain Reaction

Selection, Genetic*

Transcriptome


Find related publications in this database (Keywords)

Agriculture
Pesticide
Pollutant
Mosquito
Anopheles gambiae
Malaria
Insecticide resistance
Detoxification enzymes
Cuticle
Kdr mutation