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Forschungsdatenbank PMU-SQQUID

Pectate lyase pollen allergens: sensitization profiles and cross-reactivity pattern.
Pichler, U; Hauser, M; Wolf, M; Bernardi, ML; Gadermaier, G; Weiss, R; Ebner, C; Yokoi, H; Takai, T; Didierlaurent, A; Rafaiani, C; Briza, P; Mari, A; Behrendt, H; Wallner, M; Ferreira, F;
PLoS One. 2015; 10(5):e0120038
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Wolf Martin

Abstract

Pollen released by allergenic members of the botanically unrelated families of Asteraceae and Cupressaceae represent potent elicitors of respiratory allergies in regions where these plants are present. As main allergen sources the Asteraceae species ragweed and mugwort, as well as the Cupressaceae species, cypress, mountain cedar, and Japanese cedar have been identified. The major allergens of all species belong to the pectate lyase enzyme family. Thus, we thought to investigate cross-reactivity pattern as well as sensitization capacities of pectate lyase pollen allergens in cohorts from distinct geographic regions.


Useful keywords (using NLM MeSH Indexing)

Allergens/immunology*

Ambrosia/immunology

Animals

Antigens, Plant/immunology

Artemisia/immunology

Enzyme-Linked Immunosorbent Assay

Female

Humans

Mice

Mice, Inbred BALB C

Pollen/immunology*

Polysaccharide-Lyases/immunology*