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Forschungsdatenbank PMU-SQQUID

Assessing the reproducibility of high definition urethral pressure profilometry and its correlation with an air-charged system
Klunder, M; Amend, B; Sawodny, O; Stenzl, A; Ederer, M; Kelp, A; Sievert, KD; Feuer, R
NEUROUROL URODYNAM. 2017; 36(5): 1292-1300.
Originalarbeiten (Zeitschrift)


Sievert Karl-Dietrich


IntroductionRecently, a new urodynamic method for the assessment of stress urinary incontinence called high definition urethral pressure profilometry (HD-UPP) has been introduced. This method combines a novel microtip catheter with advanced signal processing to enable spatial data location and the reconstruction of a pressure image inside the urethra. In order to assess the reproducibility of HD-UPP data, we statistically evaluate HD-UPP datasets and compare them to data from a double balloon air-charged system. Materials and MethodsBoth catheters are used on sedated female minipigs. Data from the microtip catheter are processed through a signal reconstruction algorithm, urodynamic features are extracted, and compared to the air-charged system. Reproducibility of HD-UPP data is assessed by statistically evaluating consecutive, intra-individual datasets. ResultsHD-UPP delivers results in agreement with previous comparisons of microtip and air-charged systems. The average deviation of two consecutive, intra-individual pressure images is very low at 7cmH(2)O. ConclusionsHD-UPP provides physicians with detailed information on the pressure distribution inside the urethra. Through comparison with an air-charged catheter, it is shown that HD-UPP delivers results in agreement with previous studies on the comparison of microtip and air-charged catheters. It provides excellent reproducibility, as the difference between sequentially measured profiles from the same minipig is significantly lower than the one between profiles from different minipigs.

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digital signal processing
urinary catheters