Forschungsdatenbank PMU-SQQUID

Molecular and functional aspects of anionic channels activated during regulatory volume decrease in mammalian cells.
Fürst, J; Gschwentner, M; Ritter, M; Bottà, G; Jakab, M; Mayer, M; Garavaglia, L; Bazzini, C; Rodighiero, S; Meyer, G; Eichmüller, S; Wöll, E; Paulmichl, M;
Pflugers Arch. 2002; 444(1-2): 1-25.
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Abstract/Keywords Web of Science PubMed Full Text

PMU-Autor/inn/en

Jakab Martin
Paulmichl Markus
Ritter Markus

Abstract

The ability of cells to readjust their volume after swelling, a phenomenon known as regulatory volume decrease (RVD), is a fundamental biological achievement guaranteeing survival and function of cells under osmotic stress. This article reviews the mechanisms of RVD in mammalian cells with special emphasis on the activation of ion channels during RVD.

Useful keywords (using NLM MeSH Indexing)

Animals

Anions/metabolism*

Cell Physiological Phenomena*

Cell Size/physiology

Humans

Ion Channels/genetics

Ion Channels/physiology*

Find related publications in this database (Keywords)

RVD
VSOAC
VRAC
I(Cl,vol)
I(Cl,swell)
ORCC
RVDC
swelling