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Forschungsdatenbank PMU-SQQUID

First detection of the Anaplasma phagocytophilum groEL-A genotype in man.
Haschke-Becher, E; Bernauer, R; Walleczek, AM; Apfalter, P; Afazel-Saeedi, S; Kraus, J; Ladurner, G; Strasser, P;
J INFECTION. 2010; 60(4): 300-305.
Fallberichte

PMU-Autor/inn/en

Haschke-Becher Elisabeth
Kraus Jörg
Strasser Peter

Abstract

Human Granulocytic Anaplasmosis (HGA) is an emerging disease caused by the gram-negative bacterium Anaplasma phagocytophilum which is transmitted by ticks of the genus Ixodes ricinus. For molecular detection of the pathogen by PCR, a conserved portion of the groEL gene within the groESL operon is frequently used as a target. A single G/A polymorphism in this region allows to discriminate between two genotypes, groEL-G and groEL-A.


Useful keywords (using NLM MeSH Indexing)

Aged

Anaplasma phagocytophilum/classification*

Anaplasma phagocytophilum/genetics

Anaplasma phagocytophilum/isolation*

purification*

Anaplasmosis/diagnosis*

Anaplasmosis/microbiology

Animals

Bacterial Proteins/genetics*

Blood/microbiology

Chaperonin 60/genetics*

DNA, Bacterial/genetics

DNA, Bacterial/isolation*

purification

Female

Genotype

Humans

Male

Polymerase Chain Reaction/methods


Find related publications in this database (Keywords)

Anaplasma phagocytophilum
Human Granulocytic Anaplasmosis
groESL operon
PCR genotyping