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Forschungsdatenbank PMU-SQQUID

MR atypical Wernicke encephalopathy showing extensive brain stem and diencephalic involvement.
Nardone, R; Venturi, A; Golaszewski, S; Caleri, F; Tezzon, F; Ladurner, G;
J NEUROIMAGING. 2010; 20(2): 204-207.
Fallberichte

PMU-Autor/inn/en

Golaszewski Stefan
Nardone Raffaele

Abstract

Wernicke encephalopathy (WE) is a serious neurological disorder caused by thiamine (vitamin B1) deficiency. We report a case of atypical and extensive location of abnormal signal lesions on magnetic resonance imaging (MRI) in a man with alcohol abuse with WE. MRI performed on the first hospital day showed signal intensity alterations extending in the whole brain stem and diencephalon; the mismatch between diffusion-weighted images and apparent diffusion coefficient map was highly suggestive of vasogenic edema. This report further supports the view that WE may represent a spectrum of radiological entities and can have a wide spectrum of manifestations on MRI; thus, clinical features are essential to diagnose it.


Useful keywords (using NLM MeSH Indexing)

Alcoholism/complications*

Alcoholism/diagnosis*

Brain Stem/pathology*

Diencephalon/pathology*

Humans

Magnetic Resonance Imaging/methods*

Male

Middle Aged

Wernicke Encephalopathy/etiology*

Wernicke Encephalopathy/pathology*


Find related publications in this database (Keywords)

Wernicke encephalopathy
diencephalon
brain stem
magnetic resonance imaging
diffusion-weighted images