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Forschungsdatenbank PMU-SQQUID

Cuff-type pneumatic stimulator for studying somatosensory evoked responses with fMRI.
Gallasch, E; Fend, M; Rafolt, D; Nardone, R; Kunz, A; Kronbichler, M; Beisteiner, R; Golaszewski, S;
NEUROIMAGE. 2010; 50(3): 106-173.
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en

Golaszewski Stefan
Kronbichler Martin
Kunz Alexander
Nardone Raffaele

Abstract

For quantitative somatosensory testing in the clinical environment a microprocessor controlled MR-compatible stimulation device was developed. A main feature of this device is the use of an inflatable cuff allowing the application of defined test pressures (0-1000 mbar) to the skin surface. The cuff is pressurized by a piezoelectric proportional valve with embedded closed loop controller. The distortion of the pressure pulses, introduced by the tube between valve and cuff (tube lengths of 2 and 6 m), was evaluated. Two kinds of stimulation patterns were implemented by the microprocessor: constant frequency stimulation (selectable between 1 and 20 Hz) and stimulation with stepwise changing frequencies according to a pseudorandom sequence. imaging tests (n=8, index finger) showed more robust responses in SI (contralateral) and S2 (bilaterally) if evoked by the random sequence. Both, the technical tests and the imaging results, demonstrate that this new stimulation system is well suited to set a standard for somatosensory stimulation in individual longitudinal studies or multicenter comparisons. (C) 2010 Elsevier Inc. All rights reserved.


Useful keywords (using NLM MeSH Indexing)

Brain/physiology*

Brain Mapping/methods*

Evoked Potentials, Somatosensory*

Fingers/physiology

Humans

Magnetic Resonance Imaging/instrumentation*

Magnetic Resonance Imaging/methods

Male

Physical Stimulation

Pressure

Somatosensory Cortex/physiology

Touch Perception/physiology*


Find related publications in this database (Keywords)

Pneumatic stimulation
MRI compatible devices
Somatotopy cortex
Randomized stimulus pattern
Sensory system
Neurodiagnostics