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Forschungsdatenbank PMU-SQQUID

Transient beneficial effects of excitatory theta burst stimulation in a patient with phonological agraphia after left supramarginal gyrus infarction.
Nardone, R; De Blasi, P; Zuccoli, G; Tezzon, F; Golaszewski, S; Trinka, E;
Brain Lang. 2012; 120(3): 422-426.
Fallberichte

PMU-Autor/inn/en

Golaszewski Stefan
Nardone Raffaele
Trinka Eugen

Abstract


We report a patient showing isolated phonological agraphia after an ischemic stroke involving the left supramarginal gyrus (SMG). In this patient, we investigated the effects of focal repetitive transcranial magnetic stimulation (rTMS) given as theta burst stimulation (TBS) over the left SMG, corresponding to the Brodmann area (BA) 40. The patient and ten control subjects performed a dictational words and nonwords writing task before, and 5 and 30 min after they received excitatory intermittent TBS (iTBS) over the left BA 40, the right hemisphere homologous to BA 40, the Wernicke"s area, or the primary visual cortex. ITBS over the left SMG lead to a brief facilitation of phonological non-words writing to dictation. This case study report illustrates that rTMS is able to influence, among other language functions, the phonological loading processes during the written language production in stroke patients.


Useful keywords (using NLM MeSH Indexing)

Agraphia/pathology

Agraphia/physiopathology

Agraphia/therapy*

Cerebral Infarction/pathology

Cerebral Infarction/physiopathology

Cerebral Infarction/therapy*

Electric Stimulation Therapy/methods*

Humans

Male

Middle Aged

Parietal Lobe/pathology

Parietal Lobe/physiology*

Phonetics

Temporal Lobe/physiology

Theta Rhythm*

Transcranial Magnetic Stimulation/methods*

Visual Cortex/physiology


Find related publications in this database (Keywords)

Phonological agraphia
Stroke
Supramarginal gyrus
Transcranial magnetic stimulation
Theta burst stimulation