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Forschungsdatenbank PMU-SQQUID

Effect of person-centred care on antipsychotic drug use in nursing homes (EPCentCare): study protocol for a cluster-randomised controlled trial.
Richter, C; Berg, A; Fleischer, S; Kopke, S; Balzer, K; Fick, EM; Sonnichsen, A; Loscher, S; Vollmar, HC; Haastert, B; Icks, A; Dintsios, CM; Mann, E; Wolf, U; Meyer, G
Implement Sci. 2015; 10:82
Originalarbeiten (Zeitschrift)


Mann Eva
Sönnichsen Andreas


The majority of nursing home residents with dementia experience behavioural and psychological symptoms like apathy, agitation, and anxiety. According to analyses of prescription prevalence in Germany, antipsychotic drugs are regularly prescribed as first-line treatment of neuropsychiatric symptoms in persons with dementia, although guidelines clearly prioritise non-pharmacological interventions. Frequently, antipsychotic drugs are prescribed for inappropriate reasons and for too long without regular reviewing. The use of antipsychotics is associated with adverse events like increased risk of falling, stroke, and mortality. The aim of the study is to investigate whether a person-centred care approach, successfully evaluated in nursing homes in the United Kingdom, can be implemented in German nursing homes and, in comparison with a control group, can result in a clinically relevant reduction of the proportion of residents with antipsychotic prescriptions.

Useful keywords (using NLM MeSH Indexing)

Accidental Falls/statistics*

numerical data

Antipsychotic Agents/administration*


Antipsychotic Agents/therapeutic use

Costs and Cost Analysis


Drug Utilization


Homes for the Aged/organization*



Inservice Training

Mental Disorders/etiology

Mental Disorders/therapy*

Nursing Homes/organization*


Patient-Centered Care/organization*


Psychomotor Agitation/etiology

Psychomotor Agitation/therapy*

Quality of Life

Research Design

Find related publications in this database (Keywords)

Implementation research
Nursing homes
Antipsychotic agents
Person-centred care
Behavioural and psychological symptoms of dementia