We used transcranial magnetic stimulation (TMS) to explore if an impairment of central sensory function produced by an isolated lesion in the cervical posterior white columns would change motor cortex excitability. Cortical silent period duration was prolonged when compared with the control subjects, while central motor conduction and motor thresholds were in the normal limits. We first demonstrate that the involvement of the ascending proprioceptive sensory pathways in spinal cord diseases may have direct consequences on the activity of intracortical inhibitory interneuronal circuits. These findings further elucidate the role of afferent inputs in motor cortex reorganisation. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
Useful keywords (using NLM MeSH Indexing)
Evoked Potentials, Motor/physiology
Magnetic Resonance Imaging
Spinal Cord Injuries/pathology
Spinal Cord Injuries/physiopathology*
Transcranial Magnetic Stimulation
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