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Forschungsdatenbank PMU-SQQUID

[Transjugular intrahepatic portasystemic shunt. A new therapeutic method in portal hypertension].
Tesdal, IK; Jaschke, W; Adamus, R; Georgi, M; Filser, T; Holm, E;
Tidsskr Nor Laegeforen. 1996; 116(8): 968-972.
Originalarbeiten (Zeitschrift)


Adamus Ralf


Over the last three years, 53 patients underwent transjugular portosystemic shunting (TIPS). 49 patients were treated successfully (92.5%). Procedure-related morbidity (intention to treat) was seen in 11 patients (20.8%): encephalopathy (n = 5), sepsis (n = 3), right heart failure (n = 2) and progressive liver failure (n = 1). 30-day mortality rate was 13.2% (7/53); five of these patients were in stage Child-Pugh C, one patient in stage B, and one patient had a known coronary heart disease. 30-day rebleeding rate was 6.1% (3/49), but all these patients could be retreated successfully by radiological methods (PTA, embolisation, thrombolysis). Angiographic follow-up (mean six months) of 35 patients detected 30 (85.7%) haemodynamic relevant obstructions (stenosis of stent: n = 4, stenosis of hepatic vein: n = 15, stenosis of stent and hepatic vein: n = 5, occlusion of TIPS-shunt: n = 6). Secondary patency rate following percutaneous reintervention was 91.3%. All rebleedings in the follow-up (n = 7) were treated successfully by TIPS-revision. Five out of 12 patients (41.7%) with refractory ascites were treated successfully by TIPS (complete resolution of ascites after three months: n = 4, significant reduction of ascites: n = 1). We conclude that transjugular portosystemic shunt is an effective way of treating portal hypertension, but there is a need to develop methods to prevent the high incidence of shunt stenosis.

Useful keywords (using NLM MeSH Indexing)



Evaluation Studies as Topic


Hepatic Artery/radiography


Hypertension, Portal/radiography

Hypertension, Portal/surgery*


Middle Aged

Portasystemic Shunt, Surgical/adverse effects

Portasystemic Shunt, Surgical/contraindications

Portasystemic Shunt, Surgical/methods*