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Forschungsdatenbank PMU-SQQUID

Low level light therapy by LED of different wavelength induces angiogenesis and improves ischemic wound healing.
Dungel, P; Hartinger, J; Chaudary, S; Slezak, P; Hofmann, A; Hausner, T; Strassl, M; Wintner, E; Redl, H; Mittermayr, R
Lasers Surg Med. 2014; 46(10):773-780
Originalarbeiten (Zeitschrift)

PMU-Autor/inn/en


Abstract

Low-level light therapy (LLLT) has been revealed as a potential means to improve wound healing. So far, most studies are being performed with irradiation in the red to near-infrared spectra. Recently, we showed that blue light (470 nm) can significantly influence biological systems such as nitric oxide (NO) metabolism and is able to release NO from nitrosyl-hemoglobin or mitochondrial protein complexes. Therefore, the aim of this study was to evaluate and compare the therapeutic value of blue or red light emitting diodes (LEDs) on wound healing in an ischemia disturbed rodent flap model.


Useful keywords (using NLM MeSH Indexing)

Abdomen

Animals

Disease Models, Animal

Ischemia/etiology

Ischemia/pathology

Ischemia/radiotherapy*

Ligation

Male

Neovascularization, Physiologic/radiation effects*

Phototherapy/instrumentation*

Rats

Rats, Sprague-Dawley

Surgical Flaps/blood supply*

Wound Healing/radiation effects*


Find related publications in this database (Keywords)

angiogenesis
LED light therapy
nitric oxide
ischemic wound healing
skin flap